Results 91 to 100 of about 5,163,657 (332)
Approximation properties of simple Lie groups made discrete [PDF]
, 2015 In this paper we consider the class of connected simple Lie groups equipped with the discrete topology. We show that within this class of groups the following approximation properties are equivalent: (1) the Haagerup property; (2) weak amenability; (3 ...
Knudby, Søren, Li, Kang
core
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Embeddings into left-orderable simple groups. [PDF]
J Lond Math Soc, 2022 Darbinyan A, Steenbock M.
europepmc +1 more source
On a New Criterion for the Solvability of Non-Simple Finite Groups and m-Abelian Solvability [PDF]
, 2021 Hasan Sankari, Mohammad Abobala
openalex +1 more source
Simple endotrivial modules for quasi-simple groups [PDF]
, 2013 We investigate simple endotrivial modules of finite quasi-simple groups and classify them in several important cases. This is motivated by a recent result of Robinson showing that simple endotrivial modules of most groups come from quasi-simple groups ...
Lassueur, Caroline +2 more
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Embedding rank one simple groups into rank one simple Riesz groups [PDF]
Glasgow Mathematical Journal, 2002 We give a method for embedding a large family of partially ordered simple groups of rank one into simple Riesz groups of rank one. In particular, we answer in the affirmative a question of Wehrung, by constructing a torsion-free, simple Riesz group G of rank one containing an interval D\varsubsetneqq G^+ such that 2D=G^+.
openaire +3 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source