Results 51 to 60 of about 5,215,765 (304)

Classification of simple sequence repeats (SSRs) and expressed sequence tag-SSRs (EST-SSRs) repeats.

open access: yes, 2015
Classification of simple sequence repeats (SSRs) and expressed sequence tag-SSRs (EST-SSRs) repeats.
Jihong Hu (384604)   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

POLYMORPHISM OF INTER-SIMPLE SEQUENCE REPEATS (ISSR) IN ALLIUM SPECIES

open access: yesОвощи России, 2011
Some onion species such as A. altaicum, A. odorum, A. fistulosum, A. nutans, A. schoenoprasum, A. altissimum, A.proliferum, A. tuberosum, A. subhirsutum, A.roylei, A.auctum, A.rupestre, A.vavilovii were taken to compare each other applying ISSR markers ...
A.S. Domblides   +3 more
doaj   +1 more source

SSRMMD: A Rapid and Accurate Algorithm for Mining SSR Feature Loci and Candidate Polymorphic SSRs Based on Assembled Sequences

open access: yesFrontiers in Genetics, 2020
Microsatellites or simple sequence repeats (SSRs) are short tandem repeats of DNA widespread in genomes and transcriptomes of diverse organisms and are used in various genetic studies.
Xiangjian Gou   +11 more
doaj   +1 more source

Inter-simple sequence repeats (ISSR) primers for identification of Metarhizium majus strains.

open access: yes, 2023
Inter-simple sequence repeats (ISSR) primers for identification of Metarhizium majus strains.
Guogen Yang (15811001)   +7 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Coevolution between simple sequence repeats (SSRs) and virus genome size

open access: yesBMC Genomics, 2012
Background Relationship between the level of repetitiveness in genomic sequence and genome size has been investigated by making use of complete prokaryotic and eukaryotic genomes, but relevant studies have been rarely made in virus genomes.
Zhao Xiangyan   +11 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

SATIN: a micro and mini satellite mining tool of total genome and coding regions with analysis of perfect repeats polymorphism in coding regions

open access: yesBMC Bioinformatics
Background Tandem repeats are specific sequences in genomic DNA repeated in tandem that are present in all organisms. Among the subcategories of TRs we have Satellite repeats, that is divided into macrosatellites, minisatellites, and microsatellites ...
Carlos Willian Dias Dantas   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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