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Pathogenesis, Diseases, Immune Response, and Chemotherapy of Genus Simplexvirus

open access: yesActa Microbiologica Bulgarica, 2023
Throughout evolution, members of the genus Simplexvirus have evolved a highly effective pathoge¬netic strategy based on biomolecular interactions with pathogen-sensitive biological species. This in turn leads to pathogen-associated recurrent diseases with a wide range of clinical manifestations, including her¬petic encephalitis (HSE), herpetic ...
N. Hristova, A.S. Galabov
exaly   +2 more sources
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Fatal Simplexvirus humanalpha1 infection in howler‐monkeys (Alouatta sp.) under human care: Clinical, molecular, and pathological findings

Journal of Medical Primatology, 2023
AbstractBackgroundSimplexvirus humanalpha1 (HuAHV‐1) are common anthropozoonosis reported in marmosets but rare in howler monkeys (Alouatta sp.).MethodsNecropsy of two brown‐howler monkeys (A. caraya) and one red‐howler monkey (A. guariba clamitans) from different zoo collections were performed. Fragments of all organs were examined through microscopy.
Joanna V. Z. Echenique   +10 more
openaire   +2 more sources

Treatment With Intravenous (S)-1-[3-Hydroxy-2-(Phosphonylmethoxy)Propyl]-Cytosine Of Acyclovir-Resistant Mucocutaneous Infection With Herpes Simplexvirus In A Patient With Aids

Journal of Infectious Diseases, 1994
(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (HPMPC) is a nucleotide analogue with potent in vitro and in vivo activity against a broad range of herpesviruses, including acyclovir-resistant herpes simplex virus (HSV). A patient with severe acyclovir-resistant perineal HSV infection received intravenous HPMPC at 5 mg/kg/week, with concomitant ...
J P, Lalezari   +8 more
exaly   +3 more sources

NOVEL SIMPLEXVIRUS (SIMPLEXVIRUS DOLICHOTINEALPHA1) ASSOCIATED WITH FATALITY IN FOUR PATAGONIAN MARA (DOLICHOTIS PATAGONUM)

Journal of Zoo and Wildlife Medicine
Four of seven Patagonian maras (Dolichotis patagonum) at a zoological institution developed acute neurologic signs that progressed to tetraparesis and death. All affected were young adult females (10 mon-5 yr old) that presented over 11 d. Clinical signs were rapidly progressive and unresponsive to supportive therapies. Two of the four individuals were
Megan E, Freeman   +10 more
openaire   +2 more sources

P.468 Relation between paired immunoglobulin-like type 2 variant and herpes-simplexvirus infection in Alzheimer's disease

European Neuropsychopharmacology, 2019
S. Agostini   +3 more
openaire   +1 more source

Simplexvirus‡

2006
Bernard Roizman, Patricia L. Ward
openaire   +1 more source

Full genome sequence of bovine alphaherpesvirus 2 (BoHV-2)

Archives of Virology, 2020
Florian Pfaff   +2 more
exaly  

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