Results 51 to 60 of about 761,248 (265)

TurboPutative: A web server for data handling and metabolite classification in untargeted metabolomics

open access: yesFrontiers in Molecular Biosciences, 2022
Untargeted metabolomics aims at measuring the entire set of metabolites in a wide range of biological samples. However, due to the high chemical diversity of metabolites that range from small to large and more complex molecules (i.e., amino acids ...
Rafael Barrero-Rodríguez   +5 more
doaj   +1 more source

Synchronization and simplification

open access: yesDiscrete Mathematics, 1979
AbstractWe describe the notions of synchronization and simplification with respect to a given subsemigroup P of a semigroup S in terms of the syntactic semigroup of P. These notions derive from coding theory, which corresponds to the case where P is a free subsemigroup of a free semigroup; we apply the results to give a unified account of several ...
DE LUCA, ALDO   +3 more
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Encapsulation for Practical Simplification Procedures [PDF]

open access: yes, 2003
ACL2 was used to prove properties of two simplification procedures. The procedures differ in complexity but solve the same programming problem that arises in the context of a resolution/paramodulation theorem proving system. Term rewriting is at the core
Matlin, Olga Shumsky, McCune, William
core   +2 more sources

CAD model simplification using feature simplifications

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
We propose an enhanced method for feature-based simplification of feature-based CAD models. In previous feature-based simplification methods, a CAD model is progressively simplified by suppressing individual features with low importance one at a time, whereas in the proposed method, each feature itself is progressively simplified based on its feature ...
Yeoun YOON, Byung Chul KIM
openaire   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Simplified Integrity Checking for an Expressive Class of Denial Constraints

open access: yesAlgorithms
Data integrity is crucial for ensuring data correctness and quality and is maintained through integrity constraints that must be continuously checked, especially in data-intensive systems like OLTP.
Davide Martinenghi
doaj   +1 more source

Tax Simplification: So Necessary and So Elusive [PDF]

open access: yes, 2004
[Excerpt] Cries for tax simplification have long been heard from presidents, legislators, current and former government officials and the public. The judiciary has often expressed its frustrations in comprehending the tax statutes. The Internal Revenue
Ryesky, Kenneth H.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

BLEU is Not Suitable for the Evaluation of Text Simplification

open access: yes, 2018
BLEU is widely considered to be an informative metric for text-to-text generation, including Text Simplification (TS). TS includes both lexical and structural aspects.
Abend, Omri   +2 more
core   +1 more source

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