Results 51 to 60 of about 269,644 (356)

Dolutegravir plus rilpivirine as dual regimen in virologically suppressed HIV-1 infected patients in a clinical setting

open access: yesHIV Research & Clinical Practice, 2019
Objectives: There are scarce data on the combination of dolutegravir (DTG) plus rilpivirine (RPV) in the real world, including patients with hepatitis C virus (HCV) coinfection, toxicity or previous failure, or at risk for severe drug–drug interactions ...
Jose L. Casado   +6 more
doaj   +1 more source

Influence of Bloat Control on Relocation Rules Automatically Designed via Genetic Programming. [PDF]

open access: yesBiomimetics (Basel)
The container relocation problem (CRP) is a critical optimisation problem in maritime port operations, in which efficient container handling is essential for maximising terminal throughput.
Škalec T, Đurasević M.
europepmc   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Mythology in Children’s Literature: A Narrative Study on Roopa Pai’s Gita

open access: yesNalans, 2022
The function of conveying a culture’s myth to its younger generation is a very delicate process. Myth is a mixture of fact and fantasy and it is the duty of an adult reteller to convey the right ideas in a right manner to the children.
Rajalakshmi T, Ramya S
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The Impact of Two Types of Input Modification on EFL Reading Comprehension: Linguistic Versus Interactiona [PDF]

open access: yesTeaching English Language, 2007
This study investigates the relative effects of two types of input modification – linguistic and interactional – on Iranian EFL students' reading comprehension.
Sasan Baleghizadeh   +1 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Simplification of scientific texts: methodology and strategy

open access: yes, 2022
reservedIl presente elaborato esplora la semplificazione di testi scientifici con lo scopo di trovare le migliori tecniche e strategie per accrescere la divulgazione scientifica.
RIZZO, MARICA
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Delaunay Mesh Construction and Simplification with Feature Preserving Based on Minimal Volume Destruction

open access: yesApplied Sciences, 2022
Triangular meshes play critical roles in many applications, such as numerical simulation and additive manufacturing. However, the triangular meshes transformed from computer-aided design models using common algorithms may have many undesirable narrow ...
Yu Huo   +6 more
doaj   +1 more source

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