Results 61 to 70 of about 761,639 (265)
ClinicoEconomics and Outcomes Research, 2017 Umberto Restelli,1,2 Massimiliano Fabbiani,3 Simona Di Giambenedetto,3 Carmela Nappi,4 Davide Croce,1,2 1Centre for Research on Health Economics, Social and Health Care Management (CREMS), LIUC – Università Cattaneo, Castellanza, Italy ...
Restelli U +4 more
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Peculiarities of border control procedures’ simplification at highway border crossing points
Social Development & Security, 2023 Purpose: to reveal the peculiarities of simplification of border control procedures the Border Crossing Points (BCPs) for road traffic in the context of a sharp increase in passenger and traffic flows.
Volodymyr Andrushko +2 more
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Tax Simplification: So Necessary and So Elusive [PDF]
, 2004 [Excerpt] Cries for tax simplification have long been heard from presidents, legislators, current and former government officials and the public. The judiciary has often expressed its frustrations in comprehending the tax statutes. The Internal Revenue
Ryesky, Kenneth H.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Black-Box Optimization for Buildings and Its Enhancement by Advanced Communication Infrastructure
Advances in Distributed Computing and Artificial Intelligence Journal, 2013 The solution of repeated fixed-horizon trajectory optimization problems of processes that are either too difficult or too complex to be described by physics-based models can pose formidable challenges. Very often, soft-computing methods e.g.
Karel MACEK +3 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Ardeth, 2019 In his Il rovescio del diritto, Francesco Galgano, a master of civil law, played with the term “diritto” (law, right), pointing out that it was the only noun whose opposite does not exist.
Marco Dugato
doaj
Cluster Development and the Veiled Rise in Sonority
LanguagesChildren’s consonant cluster productions in typical and atypical phonological development were investigated for different languages reporting developmental productions that are universal, language-specific, and/or child-specific. These patterns are often
Elena Babatsouli, Eleftheria Geronikou
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