Results 161 to 170 of about 3,978 (184)

Stem Cell Culture Under Simulated Microgravity

2020
Challenging environment of space causes several pivotal alterations in living systems, especially due to microgravity. The possibility of simulating microgravity by ground-based systems provides research opportunities that may lead to the understanding of in vitro biological effects of microgravity by eliminating the challenges inherent to spaceflight ...
Muge, Anil-Inevi, Oyku, Sarigil, Melike, Kizilkaya, Gulistan, Mese, H Cumhur, Tekin, Engin, Ozcivici   +5 more
openaire   +2 more sources

Validity of microgravity simulation models on Earth

American Journal of Kidney Diseases, 2001
Many studies have used water immersion and head-down bed rest as experimental models to simulate responses to microgravity. However, some data collected during space missions are at variance or in contrast with observations collected from experimental models. These discrepancies could reflect incomplete knowledge of the characteristics inherent to each
Regnard, J, Heer, M, Drummer, C, Norsk, P   +3 more
openaire   +4 more sources

Bacillus thuringiensisConjugation in Simulated Microgravity

Astrobiology, 2009
Spaceflight experiments have suggested a possible effect of microgravity on the plasmid transfer among strains of the Gram-positive Bacillus thuringiensis, as opposed to no effect recorded for Gram-negative conjugation. To investigate these potential effects in a more affordable experimental setup, three ground-based microgravity simulators were tested:
Elise, Beuls, Rob, Van Houdt, Natalie, Leys, Camelia, Dijkstra, Oliver, Larkin, Jacques, Mahillon   +5 more
openaire   +2 more sources

Simulated microgravity upregulates an endothelial vasoconstrictor prostaglandin

Journal of Applied Physiology, 2001
Endothelial nitric oxide contributes to the vascular hyporesponsiveness to norepinephrine (NE) observed in carotid arteries from rats exposed to simulated microgravity. The goal of the present study was to determine whether a cyclooxygenase product of arachidonic acid also influences vascular responsiveness in this setting.
D S, Sangha, S, Han, R E, Purdy
openaire   +2 more sources

GASTROINTESTINAL FUNCTION IN SIMULATED SPACE FLIGHT MICROGRAVITY

Digestive and Liver Disease, 2009
S140 P. Iovino 1, G. Bilancio 2, R. Tortora1, C. Bucci 1, A. Pascariello 1 , M. Siniscalchi 1 , C. Ciacci ∗ ,1 1Università Federico II, Napoli; 2Nefrologia Seconda Università, Napoli Background and aim: Head-down bed rest condition (HDBR) is a microgravity model simulating condition of space flight.
IOVINO, Paola, BILANCIO, GIANCARLO, Tortora R, BUCCI, CRISTINA, Pascariello A, Siniscalchi M, CIACCI, Carolina   +6 more
openaire   +4 more sources

Effect of simulated microgravity on vascular contractility

Journal of Applied Physiology, 1998
Microgravity was simulated in Sprague-Dawley (SD) and Wistar (W) rats by using a tail harness to elevate the hindquarters, producing hindlimb unweighting (HU). After 20 days of HU treatment, blood vessels from both HU and control rats were cut into 3-mm rings and mounted in tissue baths for the measurement of isometric contraction.
R E, Purdy, S P, Duckles, D N, Krause, K M, Rubera, D, Sara   +4 more
openaire   +2 more sources

Response of human gut microbiota under simulated microgravity

Applied Microbiology and Biotechnology, 2022
The present study was conducted to investigate the influence of microgravity on human gut microbiota using 16S rRNA gene sequencing in vitro. The diamagnetic material magnetic levitation method was used to simulate weightless environment. The human gut microbiota was cultured under two different conditions: normal gravity (1 g), and simulated ...
Yijuan Han, Dongyan Shao, Cuicui Han, Qingsheng Huang, Wen Zhao   +4 more
openaire   +2 more sources

Body fluid metabolism at actual and simulated microgravity

Medicine &amp Science in Sports &amp Exercise, 1996
Recent observations from space missions indicate that weightlessness does not induce an increase in diuresis and natriuresis in astronauts. Rather, both oral fluid and sodium intake as well as renal fluid and sodium output appear reduced compared with the preflight condition.
Gerzer, R., Heer, M., Drummer, C.
openaire   +3 more sources

Behavior of stem cells under outer‐space microgravity and ground‐based microgravity simulation

Cell Biology International, 2015
AbstractWith rapid development of space engineering, research on life sciences in space is being conducted extensively, especially cellular and molecular studies on space medicine. Stem cells, undifferentiated cells that can differentiate into specialized cells, are considered a key resource for regenerative medicine.
Cui, Zhang, Liang, Li, Jianling, Chen, Jinfu, Wang   +3 more
openaire   +2 more sources

[Change of pulmonary circulation in microgravity and simulated microgravity].

Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering, 2002
Fluid is transferred cephalad in microgravity and simulated microgravity, and the pulmonary circulation is the first to be affected. Blood and fluid contents in the lungs increase, but unevenly distributed among various zones of the lungs. Blood vessels in the lungs are filled and distend.
L, Sun, Q L, Xiang, D S, Wang, W, Ren
openaire   +1 more source