Results 31 to 40 of about 3,978 (184)

PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity

Frontiers in Cell and Developmental Biology, 2022
The effect of cardiovascular dysfunction including orthostatic intolerance and disability on physical exercise is one of the health problems induced by long-term spaceflight astronauts face.
Chengfei Li, Yikai Pan, Yingjun Tan, Yongchun Wang, Xiqing Sun   +4 more
doaj   +1 more source

An assessment of the long-term effects of simulated microgravity on cranial neural crest cells in zebrafish embryos with a focus on the adult skeleton.

PLoS ONE, 2014
It is becoming increasingly important to address the long-term effects of exposure to simulated microgravity as the potential for space tourism and life in space become prominent topics amongst the World's governments. There are several studies examining
Sara C Edsall, Tamara A Franz-Odendaal
doaj   +1 more source

Simulated Microgravity-Induced Changes to Drug Response in Cancer Cells Quantified Using Fluorescence Morphometry

Life, 2023
Unlike plants that have special gravity-sensing cells, such special cells in animals are yet to be discovered. However, microgravity, the condition of apparent weightlessness, causes bone, muscular and immune system dysfunctions in astronauts following ...
Spencer McKinley, Adam Taylor, Conner Peeples, Megha Jacob, Gargee Khaparde, Yohan Walter, Andrew Ekpenyong   +6 more
doaj   +1 more source

The comparison of the binding parameters of silver nanoparticles to DNA in gravity and microgravity conditions [PDF]

فصلنامه علوم و فناوری فضایی, 2020
Amount of space exploration investigation has been done to understand the variations in biological structure and function of living organisms in microgravity condition.
Azadeh Hekmat, Bahar Hajati, Zahra Hajebrahimi   +2 more
doaj   +1 more source

The adaptation of Escherichia coli cells grown in simulated microgravity for an extended period is both phenotypic and genomic

npj Microgravity, 2017
Evolution: Bacteria gain advantageous mutations under simulated microgravity Bacteria grown for an extended period of time under simulated microgravity adopt growth advantages.
Madhan R. Tirumalai, Fathi Karouia, Quyen Tran, Victor G. Stepanov, Rebekah J. Bruce, C. Mark Ott, Duane L. Pierson, George E. Fox   +7 more
doaj   +1 more source

Experimental study on effect of simulated microgravity on structural chromosome instability of human peripheral blood lymphocytes. [PDF]

PLoS ONE, 2014
Experimental study was made by keeping human peripheral blood lymphocytes under simulated microgravity in a Rotary Cell Culture System bioreactor to investigate the changes that occur in the number of chromosomes, the expression rate of chromosome ...
Lijun Wei, Chuanpeng Liu, Li Kang, Yufeng Liu, Shuliang Shi, Qiong Wu, Yu Li   +6 more
doaj   +1 more source

Loss of physical contact in space alters the dopamine system in C. elegans

iScience, 2022
Summary: Progressive neuromuscular decline in microgravity is a prominent health concern preventing interplanetary human habitation. We establish functional dopamine-mediated impairments as a consistent feature across multiple spaceflight exposures and ...
Surabhi Sudevan, Kasumi Muto, Nahoko Higashitani, Toko Hashizume, Akira Higashibata, Rebecca A. Ellwood, Colleen S. Deane, Mizanur Rahman, Siva A. Vanapalli, Timothy Etheridge, Nathaniel J. Szewczyk, Atsushi Higashitani   +11 more
doaj   +1 more source

Morphological and physiological changes in mature in vitro neuronal networks towards exposure to short-, middle- or long-term simulated microgravity.

PLoS ONE, 2013
One of the objectives of the current international space programmes is to investigate the possible effects of the space environment on the crew health. The aim of this work was to assess the particular effects of simulated microgravity on mature primary ...
Giuseppe Pani, Nada Samari, Roel Quintens, Louis de Saint-Georges, Mariantonia Meloni, Sarah Baatout, Patrick Van Oostveldt, Mohammed Abderrafi Benotmane   +7 more
doaj   +1 more source

Myocardial CKIP-1 Overexpression Protects from Simulated Microgravity-Induced Cardiac Remodeling

Frontiers in Physiology, 2018
Human cardiovascular system has adapted to Earth's gravity of 1G. The microgravity during space flight can induce cardiac remodeling and decline of cardiac function.
Shukuan Ling, Yuheng Li, Guohui Zhong, Yongjun Zheng, Qing Xu, Dingsheng Zhao, Weijia Sun, Xiaoyan Jin, Hongxing Li, Jianwei Li, Huiyuan Sun, Dengchao Cao, Jinping Song, Caizhi Liu, Xinxin Yuan, Xiaorui Wu, Yinlong Zhao, Zizhong Liu, Qi Li, Yingxian Li   +19 more
doaj   +1 more source

Characterization of Human Chondrocytes Exposed to Simulated Microgravity [PDF]

Cellular Physiology and Biochemistry, 2010
Tissue engineering is a strategy of cartilage regeneration, but scaffolds, required for 3D growth of chondrocytes, are still a problem.Searching for possibilities to improve scaffold-free engineering of cartilage, we characterized human chondrocytes incubated on a random positioning machine (RPM) to simulate microgravity (microg).When cultured in ...
Ulbrich, Claudia, Westphal, Kriss, Pietsch, Jessica, Winkler, Henrik D F, Leder, Annekatrin, Bauer, Johann, Kossmehl, Peter, Grosse, Jirka, Schoenberger, Johann, Infanger, Manfred, Egli, Marcel, Grimm, Daniela   +11 more
openaire   +2 more sources