Results 41 to 50 of about 17,651 (246)

The comparison of the binding parameters of silver nanoparticles to DNA in gravity and microgravity conditions [PDF]

فصلنامه علوم و فناوری فضایی, 2020
Amount of space exploration investigation has been done to understand the variations in biological structure and function of living organisms in microgravity condition.
Azadeh Hekmat, Bahar Hajati, Zahra Hajebrahimi   +2 more
doaj   +1 more source

Experimental study on effect of simulated microgravity on structural chromosome instability of human peripheral blood lymphocytes. [PDF]

PLoS ONE, 2014
Experimental study was made by keeping human peripheral blood lymphocytes under simulated microgravity in a Rotary Cell Culture System bioreactor to investigate the changes that occur in the number of chromosomes, the expression rate of chromosome ...
Lijun Wei, Chuanpeng Liu, Li Kang, Yufeng Liu, Shuliang Shi, Qiong Wu, Yu Li   +6 more
doaj   +1 more source

Loss of physical contact in space alters the dopamine system in C. elegans

iScience, 2022
Summary: Progressive neuromuscular decline in microgravity is a prominent health concern preventing interplanetary human habitation. We establish functional dopamine-mediated impairments as a consistent feature across multiple spaceflight exposures and ...
Surabhi Sudevan, Kasumi Muto, Nahoko Higashitani, Toko Hashizume, Akira Higashibata, Rebecca A. Ellwood, Colleen S. Deane, Mizanur Rahman, Siva A. Vanapalli, Timothy Etheridge, Nathaniel J. Szewczyk, Atsushi Higashitani   +11 more
doaj   +1 more source

Spaceflight modulates gene expression in the whole blood of astronauts [PDF]

, 2016
Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their susceptibility to disease, including infectious diseases.
Barrila, Jennifer, Crabbé, Aurélie, LeBlanc, Carly, Mehta, Satish K, Nickerson, Cheryl A, Ott, C Mark, Pierson, Duane L, Stafford, Phillip   +7 more
core   +2 more sources

Effects of Sex and Gender on Adaptation to Space: Musculoskeletal Health [PDF]

, 2014
There is considerable variability among individuals in musculoskeletal response to long-duration spaceflight. The specific origin of the individual variability is unknown but is almost certainly influenced by the details of other mission conditions such ...
Bemben, Debra, Bloomfield, Susan, Hunter, Sandra K., Ploutz-Snyder, Lori, Smith, Scott M., Templeton, Kim   +5 more
core   +2 more sources

Morphological and physiological changes in mature in vitro neuronal networks towards exposure to short-, middle- or long-term simulated microgravity.

PLoS ONE, 2013
One of the objectives of the current international space programmes is to investigate the possible effects of the space environment on the crew health. The aim of this work was to assess the particular effects of simulated microgravity on mature primary ...
Giuseppe Pani, Nada Samari, Roel Quintens, Louis de Saint-Georges, Mariantonia Meloni, Sarah Baatout, Patrick Van Oostveldt, Mohammed Abderrafi Benotmane   +7 more
doaj   +1 more source

Treadmill exercise within lower body negative pressure protects leg lean tissue mass and extensor strength and endurance during bed rest. [PDF]

, 2016
Leg muscle mass and strength are decreased during reduced activity and non-weight-bearing conditions such as bed rest (BR) and spaceflight. Supine treadmill exercise within lower body negative pressure (LBNPEX) provides full-body weight loading during BR
Feiveson, Alan H, Hargens, Alan R, Lee, Stuart MC, Macias, Brandon R, Schneider, Suzanne M, Watenpaugh, Donald E   +5 more
core   +1 more source

Myocardial CKIP-1 Overexpression Protects from Simulated Microgravity-Induced Cardiac Remodeling

Frontiers in Physiology, 2018
Human cardiovascular system has adapted to Earth's gravity of 1G. The microgravity during space flight can induce cardiac remodeling and decline of cardiac function.
Shukuan Ling, Yuheng Li, Guohui Zhong, Yongjun Zheng, Qing Xu, Dingsheng Zhao, Weijia Sun, Xiaoyan Jin, Hongxing Li, Jianwei Li, Huiyuan Sun, Dengchao Cao, Jinping Song, Caizhi Liu, Xinxin Yuan, Xiaorui Wu, Yinlong Zhao, Zizhong Liu, Qi Li, Yingxian Li   +19 more
doaj   +1 more source

Characterization of Human Chondrocytes Exposed to Simulated Microgravity [PDF]

Cellular Physiology and Biochemistry, 2010
Tissue engineering is a strategy of cartilage regeneration, but scaffolds, required for 3D growth of chondrocytes, are still a problem.Searching for possibilities to improve scaffold-free engineering of cartilage, we characterized human chondrocytes incubated on a random positioning machine (RPM) to simulate microgravity (microg).When cultured in ...
Ulbrich, Claudia, Westphal, Kriss, Pietsch, Jessica, Winkler, Henrik D F, Leder, Annekatrin, Bauer, Johann, Kossmehl, Peter, Grosse, Jirka, Schoenberger, Johann, Infanger, Manfred, Egli, Marcel, Grimm, Daniela   +11 more
openaire   +2 more sources

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

Advanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam, Seon Yeong Chae, Young Woo Kwon, Hye Jin Heo, Hye Rin Lee, Ji Hyeok Lee, Dong‐Wook Han, Yun Hak Kim, Suck Won Hong   +8 more
wiley   +1 more source