Results 31 to 40 of about 4,453 (185)

Simulated Microgravity Using a Rotary Culture System Compromises the In Vitro Development of Mouse Preantral Follicles. [PDF]

PLoS ONE, 2016
Growing cells in simulated weightlessness condition might be a highly promising new technique to maintain or generate tissue constructs in a scaffold-free manner.
Shen Zhang, Dahan Zheng, Yonggen Wu, Wei Lin, Zaichong Chen, Luhe Meng, Jun Liu, Ying Zhou   +7 more
doaj   +1 more source

PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity

Frontiers in Cell and Developmental Biology, 2022
The effect of cardiovascular dysfunction including orthostatic intolerance and disability on physical exercise is one of the health problems induced by long-term spaceflight astronauts face.
Chengfei Li, Yikai Pan, Yingjun Tan, Yongchun Wang, Xiqing Sun   +4 more
doaj   +1 more source

Myocardial CKIP-1 Overexpression Protects from Simulated Microgravity-Induced Cardiac Remodeling

Frontiers in Physiology, 2018
Human cardiovascular system has adapted to Earth's gravity of 1G. The microgravity during space flight can induce cardiac remodeling and decline of cardiac function.
Shukuan Ling, Yuheng Li, Guohui Zhong, Yongjun Zheng, Qing Xu, Dingsheng Zhao, Weijia Sun, Xiaoyan Jin, Hongxing Li, Jianwei Li, Huiyuan Sun, Dengchao Cao, Jinping Song, Caizhi Liu, Xinxin Yuan, Xiaorui Wu, Yinlong Zhao, Zizhong Liu, Qi Li, Yingxian Li   +19 more
doaj   +1 more source

The Impact of Simulated Microgravity on Mice With Breast Cancer [PDF]

فصلنامه علوم و فناوری فضایی
Exposure to microgravity induces significant changes in the morphology and biological properties of cancer cells. Globally, breast cancer is the most prevalent cancer among women and the fifth leading cause of cancer-related deaths. Increasing resistance
Morteza Alemi, Firooz Samadi, Alireza Madjid Ansari, Zahra Hajebrahimi   +3 more
doaj   +1 more source

Pectin methylesterase gene AtPMEPCRA contributes to physiological adaptation to simulated and spaceflight microgravity in Arabidopsis

iScience, 2022
Summary: Pectin is biosynthesized in a highly methylated form and is partially de-methylated by pectin methylesterase (PME) activity. Plant PMEs play a critical role in cell wall remodeling in many physiological processes.
Peipei Xu, Haiying Chen, Jinbo Hu, Xiaocheng Pang, Jing Jin, Weiming Cai   +5 more
doaj   +1 more source

Simulated microgravity-induced aortic remodeling

Journal of Applied Physiology, 2009
We have previously shown that microgravity and simulated microgravity induce an increase in human and rat aortic stiffness. We attempted to elucidate the mechanism(s) responsible for this increase in stiffness. We hypothesize that an alteration in vessel wall collagen or elastin content or in extracellular matrix (ECM) cross-linking either individually
Eric C, Tuday, Daniel, Nyhan, Artin A, Shoukas, Dan E, Berkowitz   +3 more
openaire   +3 more sources

The Growth of Soybean (Glycine max) Under Salt Stress Is Modulated in Simulated Microgravity Conditions

Cells
The role of a simulated microgravity environment on soybean growth was investigated. The root grew more under simulated microgravity conditions than in the presence of gravity.
Setsuko Komatsu, Haruka Misaki, Wei Zhu, Hisateru Yamaguchi, Keisuke Hitachi, Kunihiro Tsuchida, Atsushi Higashitani   +6 more
doaj   +1 more source

Simulated Microgravity Modulates Differentiation Processes of Embryonic Stem Cells

Cellular Physiology and Biochemistry, 2016
Background/Aims: Embryonic developmental studies under microgravity conditions in space are very limited. To study the effects of altered gravity on the embryonic development processes we established an in vitro methodology allowing differentiation of ...
Vaibhav Shinde, Sonja Brungs, Margit Henry, Lucia Wegener, Harshal Nemade, Tamara Rotshteyn, Aviseka Acharya, Christa Baumstark-Khan, Christine E. Hellweg, Jürgen Hescheler, Ruth Hemmersbach, Agapios Sachinidis   +11 more
doaj   +1 more source

Morphological and physiological changes in mature in vitro neuronal networks towards exposure to short-, middle- or long-term simulated microgravity.

PLoS ONE, 2013
One of the objectives of the current international space programmes is to investigate the possible effects of the space environment on the crew health. The aim of this work was to assess the particular effects of simulated microgravity on mature primary ...
Giuseppe Pani, Nada Samari, Roel Quintens, Louis de Saint-Georges, Mariantonia Meloni, Sarah Baatout, Patrick Van Oostveldt, Mohammed Abderrafi Benotmane   +7 more
doaj   +1 more source

TRPC6 in simulated microgravity of intervertebral disc cells [PDF]

European Spine Journal, 2018
Purpose Prolonged bed rest and microgravity in space cause intervertebral disc (IVD) degeneration. However, the underlying molecular mechanisms are not completely understood. Transient receptor potential canonical (TRPC) channels are implicated in mechanosensing of several tissues, but are poorly explored in IVDs.
Franco-Obregón A., Cambria E., Greutert H., Wernas T., Hitzl W., Egli M., Sekiguchi M., Boos N., Hausmann O., Ferguson S.J., Kobayashi H., Wuertz-Kozak K.   +11 more
openaire   +5 more sources