Results 71 to 80 of about 17,651 (246)

Overexpression of catalase in mitochondria mitigates changes in hippocampal cytokine expression following simulated microgravity and isolation

npj Microgravity, 2021
Isolation on Earth can alter physiology and signaling of organs systems, including the central nervous system. Although not in complete solitude, astronauts operate in an isolated environment during spaceflight.
Linda Rubinstein, Ann-Sofie Schreurs, Samantha M. Torres, Sonette Steczina, Moniece G. Lowe, Frederico Kiffer, Antiño R. Allen, April E. Ronca, Marianne B. Sowa, Ruth K. Globus, Candice G. T. Tahimic   +10 more
doaj   +1 more source

Untargeted Lipidomics of Erythrocytes under Simulated Microgravity Conditions

International Journal of Molecular Sciences, 2023
Lipidomics and metabolomics are nowadays widely used to provide promising insights into the pathophysiology of cellular stress disorders. Our study expands, with the use of a hyphenated ion mobility mass spectrometric platform, the understanding of the cellular processes and stress due to microgravity.
Manis, Cristina, Murgia, Antonio, Manca, Alessia, Pantaleo, Antonella, Cao, Giacomo, Caboni, Pierluigi   +5 more
openaire   +3 more sources

Sampling, Mobility, and Anchoring in Small‐Body Sampling Robots: A Comprehensive Review

SmartBot, EarlyView.
Small‐body sampling robots are exploration systems that perform contact, sampling, and stable operations on microgravity bodies such as asteroids and comets. The authors review representative robot architectures and key technologies, focusing on the mechanisms, evolution, and coupling of sampling, mobility, and anchoring.
Yurui Shen, Yixin Zhu, Mingxia Bao, Ting Zhang, Jun Wu, Jingbin Hao, Dezheng Hua, Xinhua Liu   +7 more
wiley   +1 more source

An atomic force microscope operating at hypergravity for in situ measurement of cellular mechano-response [PDF]

, 2009
We present a novel atomic force microscope (AFM) system, operational in liquid at variable gravity, dedicated to image cell shape changes of cells in vitro under hypergravity conditions. The hypergravity AFM is realized by mounting a stand-alone AFM into
Hulst, N.F. van, Jong, H.H.A. de, Korterik, J.P., Laar, M.C. van, Loon, J.J.W.A. van, Segerink, F.B., Wubbels, R.J.   +6 more
core   +2 more sources

Simulated microgravity decreases apoptosis in fetal fibroblasts

International Journal of Molecular Medicine, 2012
Space travel is a major challenge for human beings. Especially, the mechanisms through which space conditions might alter animal development have been questioned for a long time. The two major physical stress factors that are of relevance in this context are space radiation and weightlessness.
Michaël, Beck, Kevin, Tabury, Marjan, Moreels, Paul, Jacquet, Patrick, Van Oostveldt, Winnok H, De Vos, Sarah, Baatout   +6 more
openaire   +3 more sources

Technologized Reproduction in Space: A Space‐Bioethical Case for Assisted Procreation

Bioethics, EarlyView.
ABSTRACT With the increasing feasibility of space colonization, the issue of reproduction in space is becoming more relevant. As new settlements on the Moon, Mars, and other celestial bodies emerge, ensuring generational continuity will be essential for the survival and growth of these communities.
Maurizio Balistreri, Konrad Szocik
wiley   +1 more source

Under simulated microgravity and gravity, anthocyanin is regulated by DcaWRKY2 in Dendrobium catenatum leaves

Frontiers in Plant Science
Long-term space missions will require high-quality plants that are edible, medicinal, and ornamental, to support the physical and mental health of astronauts under altered gravity conditions.
Tianze Hou, Baoqiang Zheng, Fucheng Peng, Zehui Jiang, Wenbo Zhang, Yan Wang   +5 more
doaj   +1 more source

The futuristic manifolds of REM sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since one of its first descriptions 70 years ago, rapid eye movement sleep has continually inspired and excited new generations of sleep researchers. Despite significant advancements in understanding its neurocircuitry, underlying mechanisms and microstates, many questions regarding its function, especially beyond the early neurodevelopment ...
Liborio Parrino, Ivana Rosenzweig
wiley   +1 more source

Effect of change in spindle structure on proliferation inhibition of osteosarcoma cells and osteoblast under simulated microgravity during incubation in rotating bioreactor. [PDF]

PLoS ONE, 2013
In order to study the effect of microgravity on the proliferation of mammalian osteosarcoma cells and osteoblasts, the changes in cell proliferation, spindle structure, expression of MAD2 or BUB1, and effect of MAD2 or BUB1 on the inhibition of cell ...
Lijun Wei, Yan Diao, Jing Qi, Alexander Khokhlov, Hui Feng, Xing Yan, Yu Li   +6 more
doaj   +1 more source

Is sleep affected after microgravity and hypergravity exposure? A pilot study

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is known to be affected in space travel and in residents of the international space station. But little is known about the direct effects of gravity changes on sleep, if other factors, such as sleep conditions, are kept constant. Here, as a first exploration, we investigated sleep before and after exposure to short bouts of microgravity ...
Barbara Le Roy, Aurore Jouvencel, Anika Friedl‐Werner, Ludmila Renel, Youcef Cherchali, Raouf Osseiran, Ernesto Sanz‐Arigita, Jean‐René Cazalets, Etienne Guillaud, Ellemarije Altena   +9 more
wiley   +1 more source