Results 41 to 50 of about 409,298 (297)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Perceived Benefits of a Standardized Patient Simulation in Pre-Placement Dietetic Students

open access: yesEducation Sciences, 2020
The purpose of this study was to evaluate the effect of a simulation-based learning (SBL) experience on perceived confidence in monitoring and evaluation, as part of the delivery of nutrition care of pre-placement dietetic students, and to describe their
Hattie H. Wright   +3 more
doaj   +1 more source

New hardware platforms for healthcare consultations [PDF]

open access: yes, 2010
Innovative hardware platforms such as Mobile Clinical Assistants and tabletop computers are emerging that have the potential to significantly impact the interaction between clinician and patient.
Randell, R., Wilson, S.
core  

Application of Basic Pharmacology and Dispensing Practice of Antibiotics in Accredited Drug-Dispensing Outlets in Tanzania. [PDF]

open access: yes, 2013
Provision of pharmaceutical services in accredited drug-dispensing outlets (ADDOs) in Tanzania has not been reported. This study compared the antibiotics dispensing practice between ADDOs and part II shops, or duka la dawa baridi (DLDBs), in Tanzania ...
Manyilizu, Vs, Minzi, Om
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Automated capture and transfer of human facial expressions to humanoid robots for realistic patient simulation

open access: yesFrontiers in Robotics and AI
Realistic reproduction of human facial expressions is essential for realistic interactions between humans and humanoid robots. This work presents a data-driven framework for transferring human facial expressions to a humanoid robot and a virtual avatar ...
Patricia Schwarz   +6 more
doaj   +1 more source

Radiotherapy planning for glioblastoma based on a tumor growth model: Improving target volume delineation [PDF]

open access: yes, 2013
Glioblastoma are known to infiltrate the brain parenchyma instead of forming a solid tumor mass with a defined boundary. Only the part of the tumor with high tumor cell density can be localized through imaging directly.
Ayache, Nicholas   +6 more
core   +5 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

A simulated patient study to evaluate community pharmacist assessment, management and advice giving to patients with asthma

open access: yesJournal of Pharmaceutical Policy and Practice, 2021
Background Research has shown that there is an increase in the global prevalence of asthma. Pharmacists are well positioned to screen and refer patients for better management of asthma.
Sanah Hasan   +2 more
doaj   +1 more source

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