Results 51 to 60 of about 406,164 (300)

A simulated patient study to evaluate community pharmacist assessment, management and advice giving to patients with asthma

Journal of Pharmaceutical Policy and Practice, 2021
Background Research has shown that there is an increase in the global prevalence of asthma. Pharmacists are well positioned to screen and refer patients for better management of asthma.
Sanah Hasan, Lujain Al Oum, Nageeb AbdulGalil Hassan   +2 more
doaj   +1 more source

Can virtual nature improve patient experiences and memories of dental treatment? A study protocol for a randomized controlled trial [PDF]

, 2014
Background Dental anxiety and anxiety-related avoidance of dental care create significant problems for patients and the dental profession. Distraction interventions are used in daily medical practice to help patients cope with unpleasant procedures ...
Andrade, J, Auvray, M, Bruce, M, Gabe, R, May, J, Mills, I, Moles, DR, Pahl, S, Stone, RJ, Tanja-Dijkstra, K, White, MP   +10 more
core   +4 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The 2024 French guidelines for scenario design in simulation-based education: manikin-based immersive simulation, simulated participant-based immersive simulation and procedural simulation

Medical Education Online
Background Simulation-based education in healthcare encompasses a wide array of modalities aimed at providing realistic clinical experiences supported by meticulously designed scenarios. The French-speaking Society for Simulation in Healthcare (SoFraSimS)
Guillaume Der Sahakian, Maxime de Varenne, Clément Buléon, Guillaume Alinier, Christian Balmer, Antonia Blanié, Bertrand Bech, Anne Bellot, Hamdi Boubaker, Nadège Dubois, Francisco Guevara, Erwan Guillouet, Jean-Claude Granry, Morgan Jaffrelot, François Lecomte, Fernande Lois, Mohammed Mouhaoui, Ollivier Ortolé, Méryl Paquay, Justine Piazza, Marie Pittaco, Patrick Plaisance, Dan Benhamou, Gilles Chiniara, Etienne Rivière   +24 more
doaj   +1 more source

Effects of using a cognitive aid on content and feasibility of debriefings of simulated emergencies

GMS Journal for Medical Education, 2021
Background: Adverse events in patient care are often caused by failures in teamwork. Simulation training and its debriefing can contribute to improving teamwork and thus patient care. When conducting debriefings, there are several design factors that can
Freytag, Julia, Stroben, Fabian, Hautz, Wolf E., Penders, Dorothea, Kämmer, Juliane E.   +4 more
doaj   +1 more source

Artificial neural network-statistical approach for PET volume analysis and classification [PDF]

, 2012
Copyright © 2012 The Authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.This ...
Abbod, Maysam, Abbod, Maysam, Amira, Abbes, Amira, Abbes, Sharif, M., Sharif, M., Zaidi, Habib, Zaidi, Habib   +7 more
core   +4 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Unconstrained video monitoring of breathing behavior and application to diagnosis of sleep apnea [PDF]

, 2014
This paper presents a new real-time automated infrared video monitoring technique for detection of breathing anomalies, and its application in the diagnosis of obstructive sleep apnea.
Gravill, N., Hunter, A., Matusiewicz, S., Wang, C.-W.   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source