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Simulated Weightlessness Perturbs the Intestinal Metabolomic Profile of Rats [PDF]

open access: yesFrontiers in Physiology, 2019
Recently, disorders of intestinal homeostasis in the space environment have been extensively demonstrated. Accumulating evidence have suggested microgravity and simulated weightlessness could induce dysbiosis of intestinal microbiota, which may ...
Ke Zhao
exaly   +7 more sources

Sensorimotor performance and haptic support in simulated weightlessness [PDF]

open access: hybridExperimental Brain Research, 2020
AbstractThe success of many space missions critically depends on human capabilities and performance. Yet, it is known that sensorimotor performance is degraded under conditions of weightlessness. Therefore, astronauts prepare for their missions in simulated weightlessness under water.
Bernhard Weber   +2 more
exaly   +8 more sources

Objects Mental Rotation under 7 Days Simulated Weightlessness Condition: An ERP Study [PDF]

open access: goldFrontiers in Human Neuroscience, 2017
During the spaceflight under weightlessness condition, human's brain function may be affected by the changes of physiological effects along with the distribution of blood and body fluids to the head.
Wang H   +5 more
exaly   +6 more sources

Responses of Intestinal Mucosal Barrier Functions of Rats to Simulated Weightlessness [PDF]

open access: yesFrontiers in Physiology, 2018
Exposure to microgravity or weightlessness leads to various adaptive and pathophysiological alterations in digestive structures and physiology. The current study was carried out to investigate responses of intestinal mucosal barrier functions to ...
Mingliang Jin, Ke Zhao, Chunlan Xu
exaly   +8 more sources

Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness. [PDF]

open access: goldFront Physiol, 2023
Objective: Microgravity contributes to ocular injury yet the underlying mechanism remains unclear. This study aims to elucidate the mechanism behind choroidal circulation disorder and outer retinal degeneration in rats with simulated weightlessness ...
Mu Y   +7 more
europepmc   +4 more sources

Simulated weightlessness procedure, head-down bed rest has reversible effects on the metabolism of rhesus macaque. [PDF]

open access: goldMol Brain
It is a consensus in the international manned space field that factors such as microgravity during the space flight can cause anxiety, depression and other important brain function abnormalities in astronauts.
Li Y   +16 more
europepmc   +3 more sources

Dammarane Sapogenins Improving Simulated Weightlessness-Induced Depressive-Like Behaviors and Cognitive Dysfunction in Rats. [PDF]

open access: goldFront Psychiatry, 2021
Background: Our studies demonstrated that the space environment has an impact on the brain function of astronauts. Numerous ground-based microgravity and social isolation showed that the space environment can induce brain function damages in humans and ...
Wang Q   +11 more
europepmc   +4 more sources

Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions. [PDF]

open access: goldNeural Regen Res
A microgravity environment has been shown to cause ocular damage and affect visual acuity, but the underlying mechanisms remain unclear. Therefore, we established an animal model of weightlessness via tail suspension to examine the pathological changes ...
Mu Y   +9 more
europepmc   +3 more sources

Effects of real and simulated weightlessness on the cardiac and peripheral vascular functions of humans: A review [PDF]

open access: goldInternational Journal of Occupational Medicine and Environmental Health, 2015
Weightlessness is an extreme environment that can cause a series of adaptive changes in the human body. Findings from real and simulated weightlessness indicate altered cardiovascular functions, such as reduction in left ventricular (LV) mass, cardiac ...
Hui Zhu, Zhiqiang Liu
exaly   +4 more sources

Morphology and Molecular Mechanisms of Hepatic Injury in Rats under Simulated Weightlessness and the Protective Effects of Resistance Training. [PDF]

open access: goldPLoS One, 2015
This study investigated the effects of long-term simulated weightlessness on liver morphology, enzymes, glycogen, and apoptosis related proteins by using two-month rat-tail suspension model (TS), and liver injury improvement by rat-tail suspension with ...
Du F   +9 more
europepmc   +4 more sources

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