Results 51 to 60 of about 2,371,814 (293)

Dissolution of Microalloying Elements in a Ladle Metallurgy Furnace

open access: yesMetals, 2023
Industrial fusion of microalloying elements in steelmaking is imperative in defining and optimizing certain steel properties due to their strengthening and significant grain refinements effects at minute quantities.
Ogochukwu Queeneth Duruiheme   +3 more
doaj   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Robotic Simulations, Simulations of Robots

open access: yesMinds and Machines, 2019
Simulation studies have been carried out in robotics for a variety of epistemic and practical purposes. Here it is argued that two broad classes of simulation studies can be identified in robotics research. The first one is exemplified by the use of robotic systems to acquire knowledge on living systems in so-called biorobotics, while the second class ...
V. Schiaffonati, DATTERI, EDOARDO
openaire   +2 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

The chiral Hall effect in canted ferromagnets and antiferromagnets

open access: yesCommunications Physics, 2021
The Hall effect is about the generation of a transverse voltage when a longitudinal current is applied and many mechanisms can lead to Hall effect in magnetic material. Here, the authors report a chiral Hall effect that is proportional to the vector spin
Jonathan Kipp   +10 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Research and Realization of the Simulation Test System for Train Control On-board Equipment

open access: yes机车电传动, 2017
Aiming at the requirement of simulation test to train control on-board equipment, the overall technical scheme and the realization method of the simulation test system for train control on-board equipment were presented by analyzing the running ...
Research and Realization of the Simulation Test System for Train Control On-board Equipment
doaj  

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

open access: yesMolecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun   +5 more
wiley   +1 more source

Promoting leadership and communication skills in emergency medicine residents: the role of High-Fidelity Simulation

open access: yesEmergency Care Journal
The residency program in Emergency Medicine should include formal training in Non-Technical Skills (NTS). We evaluated the effectiveness of a program based on High-Fidelity Simulation (HFS) to improve the leadership and communication skills of residents
Lorenzo Maiorano   +9 more
doaj   +1 more source

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