Results 101 to 110 of about 1,786,466 (304)

Numerical simulation and experimental validation of texture in extruded wires of a bcc metal [PDF]

, 2013
We present a comparison between a viscoplastic crystal plasticity finite element simulation of the extrusion process applied to a bcc polycrystal and the experimental evaluation of the preferred orientation (texture) in a tungsten wire by monochromatic ...
Bainpas, Nikolaos, Korsunsky, Alexander M., Reinhard, Christina, Xie, Mengyin   +3 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Validating Forward Modeling and Inversions of Helioseismic Holography Measurements

, 2018
Here we use synthetic data to explore the performance of forward models and inverse methods for helioseismic holography. Specifically, this work presents the first comprehensive test of inverse modeling for flows using lateral-vantage (deep-focus ...
Birch, A. C., Braun, D. C., Crouch, A. D., DeGrave, K., Javornik, B.   +4 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Dynamics in a supercooled molecular liquid: Theory and Simulations

, 2000
We report extensive simulations of liquid supercooled states for a simple three-sites molecular model, introduced by Lewis and Wahnstr"om [L. J. Lewis and G. Wahnstr"om, Phys. Rev. E 50, 3865 (1994)] to mimic the behavior of ortho-terphenyl.
A. Heuer, A. Tölle, A. Winkler, Adele Rinaldi, B. Doliwa, B. J. Alder, C. Donati, C. Masciovecchio, C. Theis, C. Theis, D. J. Plazek, D. Morineau, D. Morineau, E. Bartsch, E. La Nave, F. Sciortino, F. Sciortino, F. Sciortino, F. Sciortino, F. Sciortino, F. Sciortino, F. Sciortino, F. W. Starr, Francesco Sciortino, G. Monaco, G. Monaco, G. Wahnström, J. Horbach, J. P. Hansen, J. Wuttke, J.-L. Barrat, L. Angelani, L. Fabbian, L. Fabbian, L. Fabbian, L. Fabbian, L. J. Lewis, M. C. Ribeiro, M. Fuchs, M. Nauroth, P. Gallo, Piero Tartaglia, R. Schilling, S. Büchner, S. K. Lai, S. Kämmerer, S. Mossa, S. Sastri, S.-H. Chong, S.-H. Chong, S.-H. Chong, T. Franosch, T. Scheidsteger, W. Gotze, W. Götze, W. Kob, W. Kob, W. Petry   +57 more
core   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

An Ultrafast Image Simulation Technique with Spatially Variable Point-spread Functions

The Astronomical Journal
Simulated images are essential in algorithm development and instrument testing for optical telescopes. During real observations, images obtained by optical telescopes are affected by spatially variable point-spread functions (PSFs), a crucial effect ...
Zeyu Bai, Peng Jia, Jiameng Lv, Xiang Zhang, Wennan Xiang, Lin Nie   +5 more
doaj   +1 more source

Towards the application of the Maximum Entropy Method to finite temperature Upsilon Spectroscopy

, 2000
According to the Narnhofer Thirring Theorem interacting systems at finite temperature cannot be described by particles with a sharp dispersion law. It is therefore mandatory to develop new methods to extract particle masses at finite temperature.
Bryan, C. Davies, Davies, de Forcrand, Huang, J. Shigemitsu, Jarrel, M. Oevers, Nakahara, Nakahara, Requard, Skilling   +11 more
core   +2 more sources