Results 51 to 60 of about 1,786,466 (304)
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Nonlocal peridynamic method for porous media seepage simulation
Rock and Soil Mechanics, 2021 Based on the establishment of peridynamic nonlocal porous media seepage model, several kernel functions reflecting the degree of nonlocal effect are introduced to improve the calculation accuracy, and the peridynamic permeability coefficients ...
MA Peng-fei +5 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Optimization of Excitation in FDTD Method and Corresponding Source Modeling [PDF]
, 2015 Source and excitation modeling in FDTD formulation has a significant impact on the method performance and the required simulation time. Since the abrupt source introduction yields intensive numerical variations in whole computational domain, a generally ...
Aleksic, S. +3 more
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Numerical Simulation of Time Fractional BBM-Burger Equation Using Cubic B-Spline Functions
Journal of Function Spaces, 2022 The unidirectional propagation of long waves in certain nonlinear dispersive system is explained by the Benjamin-Bona-Mahony-Burger (BBM-Burger) equation.
Mohsin Kamran +4 more
doaj +1 more source
Non-Gaussian Features of Transmitted Flux of QSO's Ly$\alpha$ Absorption: Intermittent Exponent
, 2002 We calculate the structure function and intermittent exponent of the 1.) Keck data, which consists of 29 high resolution, high signal to noise ratio (S/N) QSO Ly$\alpha$ absorption spectra, and 2.)the Ly$\alpha$ forest simulation samples produced via the
Batchelor G. K. +10 more
core +1 more source
Stochastic wave-function simulation of two-time correlation functions [PDF]
Journal of Modern Optics, 1999 17 pages, 3 EPS ...
Felbinger, Timo +1 more
openaire +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source