Results 71 to 80 of about 4,227,869 (356)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Enhanced Buck Converter with Universal Model for the Switched Voltage Regulators

open access: yesCommunications
This article presents the enhancement and refinement of a simulation model for an integrated universal switched voltage regulator compatible with PSPICE software.
Dobroslav Kováč, Irena Kováčová
doaj   +1 more source

Contrail Modeling and Simulation [PDF]

open access: yesAnnual Review of Fluid Mechanics, 2016
There is large uncertainty in the radiative forcing induced by aircraft contrails, particularly after they transform to cirrus. It has recently become possible to simulate contrail evolution for long periods after their formation. We review the main physical processes and simulation efforts in the four phases of contrail evolution, namely the jet ...
Roberto Paoli, Karim Shariff
openaire   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Assessing the Risks of a Freight Forwarder Entering the Transport Market with Stochastic Demand

open access: yesCommunications
This research investigates freight forwarders' operational risks when entering a new transport market characterized by stochastic demand. A simulation model was developed to represent the service request flow potentially experienced by a freight ...
Vitalii Naumov   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Simulation Model for Foreign Trade During the Crisis in Romania

open access: yesRomanian Economic Journal, 2014
The paper proposes to analyze the evolution of foreign trade during the crisis in Romania. The evolution of foreign trade is analyzed using a simulation model. The period of analysis is 2006-2014. The data source is Eurostat and National Bank of Romania.
Mirela Diaconescu   +2 more
doaj  

GAMMA; a simulation model for ageing, pensions and public finances [PDF]

open access: yes
To answer policy questions that have intergenerational implications, a computable simulation model should obey four conditions, it should: incorporate long-term demographic developments; include a detailed modelling of the public sector; decompose the ...
Alex Armstrong, Nick Draper
core  

Development of a DC-DC buck boost converter using fuzzy logic control [PDF]

open access: yes, 2011
A fuzzy controller of DC-DC Buck-boost converter is designed and presented in this project. In order to control the output voltage of the buck-boost converter, the controller is designed to change the duty cycle of the converter. The mathematical model
Shaban Jaber, Fathi
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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