Results 51 to 60 of about 4,227,869 (356)

A Simulation Model of the Logistics System of a Small Enterprise [PDF]

open access: yesProblemi Ekonomiki, 2017
An important trend in the theoretical study of the current activity and strategic prospects of small enterprises is the development of dynamic models of their functioning under the contemporary socio-economic conditions.
Sherstennykov Yuriy V.
doaj  

Influence of vehicle acceleration intensity on dual-mass flywheel elements and transmission load

open access: yesTransport Technologies, 2022
Modern high-torque low-speed internal combustion engines (ICEs) generate torsional vibrations close in disturbance frequency to gearboxes natural oscillation frequencies. Effective absorption of such oscillations requires a new torsional vibration damper
Bohdan Kindratskyy   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Quantitative systems pharmacology model of B cell immune response in mouse

open access: yesFrontiers in Immunology
B cell-mediated immunity plays a crucial role in long-term humoral protection. However, dysregulation of B cell development and differentiation may lead to the persistence of autoreactive clones, contributing to autoimmune diseases.
Yaroslav Ugolkov   +10 more
doaj   +1 more source

The Model of Decision Support to Prevent the Transmission of a Financial Crisis to the Real Economy [PDF]

open access: yesProblemi Ekonomiki, 2018
The aim of the article is to form an integrated model to forecast, identify a financial crisis and minimize its spread to the real economy. The conceptual scheme reflecting the investigation of the transmission of a financial crisis to the real economy ...
Poliakova Olha Yu.   +1 more
doaj  

Ecohydraulics Modelling and Simulation [PDF]

open access: yesWater, 2021
Ecohydraulics, the interdiscipline of ecology and hydraulics, has been rapidly developing and receiving ever-growing attention both in hydraulic research efforts and in environmentally oriented professional and lay communities in recent years [...]
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

THE METHOD OF DESIGNING HYDRAULIC DRIVES ON THE EXAMPLE OF A HYDRAULIC DRIVE OF A LIFTING-MAST DEVICE

open access: yesСистемный анализ и прикладная информатика, 2018
The classical approach to the design of hydraulic drives includes complex calculations and real tests, which is a resource-consuming process. Reduce the cost of design allows the introduction of the development of simulation modeling and CAD / CAM / CAE /
S. A. Smirnov, N. A. Gorshkova
doaj   +1 more source

GHG Emissions from Dairy Small Ruminants in Castilla-La Mancha (Spain), Using the ManleCO2 Simulation Model

open access: yesAnimals, 2022
The first goal of this work was the description of a model addressed to quantify the carbon footprint in Spanish autochthonous dairy sheep farms (Manchega group), foreign dairy sheep farms (foreigners group: Lacaune and Assaf breeds), and Spanish ...
Gregorio Salcedo   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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