Results 41 to 50 of about 16,427,470 (298)
CPT: Pharmacometrics & Systems PharmacologyIn 2017, the free and open‐source software Open Systems Pharmacology (OSP) was launched. Since then, OSP has evolved from a small community into a diverse network of stakeholders committed to advancing open‐source solutions for model‐informed drug ...
André Dallmann +31 more
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MetabolitesBackground/Objectives: Mesoporous silica nanoparticles (MSNs) are widely investigated as nanocarriers for drug delivery, gene transfer, and bioimaging.
Jing Li, Hui Xu
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Influence of vehicle acceleration intensity on dual-mass flywheel elements and transmission load
Transport Technologies, 2022 Modern high-torque low-speed internal combustion engines (ICEs) generate torsional vibrations close in disturbance frequency to gearboxes natural oscillation frequencies. Effective absorption of such oscillations requires a new torsional vibration damper
Bohdan Kindratskyy +2 more
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Simulation of econometric models [PDF]
Proceedings of the 6th conference on Winter simulation, 1973 The purposes of this tutorial are to present some fundamental properties of econometric model structures relevant to effective understanding of simulation procedures, and to describe the use of simulation software for analysis and forecasting.The fundamental concepts of model specification are developed formally to provide a logical foundation for ...
openaire +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Системный анализ и прикладная информатика, 2018 The classical approach to the design of hydraulic drives includes complex calculations and real tests, which is a resource-consuming process. Reduce the cost of design allows the introduction of the development of simulation modeling and CAD / CAM / CAE /
S. A. Smirnov, N. A. Gorshkova
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Animals, 2022 The first goal of this work was the description of a model addressed to quantify the carbon footprint in Spanish autochthonous dairy sheep farms (Manchega group), foreign dairy sheep farms (foreigners group: Lacaune and Assaf breeds), and Spanish ...
Gregorio Salcedo +5 more
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FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Simulation of collective action based on empirical data
, 2004 Taking collective action as an example, the paper shows that ABS is particularly well suited for representation and explanation of the emergence of dynamic processes out of the interaction of different processes at multiple levels.
Mosler, Hans-Joachim (author) +1 more
core +1 more source