Results 31 to 40 of about 1,873,107 (281)

Mimosa: Using ontologies for modeling and simulation [PDF]

open access: yes, 2007
Modeling is the shared activity for both modeling and simulation, and knowledge representation. At the same time, the objectives of these two domains are not the same and both seem necessary when dealing with modeling highly structured and complex ...
Müller, Jean Pierre
core   +2 more sources

Internet-of-Things Devices in Support of the Development of Echoic Skills among Children with Autism Spectrum Disorder

open access: yesSensors, 2021
A significant therapeutic challenge for people with disabilities is the development of verbal and echoic skills. Digital voice assistants (DVAs), such as Amazon’s Alexa, provide networked intelligence to billions of Internet-of-Things devices and have ...
Krzysztof J. Rechowicz   +4 more
doaj   +1 more source

Software that goes with the flow in systems biology [PDF]

open access: yes, 2010
A recent article in BMC Bioinformatics describes new advances in workflow systems for computational modeling in systems biology. Such systems can accelerate, and improve the consistency of, modeling through automation not only at the simulation and ...
A Funahashi   +14 more
core   +3 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Population Pharmacokinetics of Bepirovirsen in Healthy Participants and Participants with Chronic Hepatitis B Virus Infection: Results from Phase 1, 2a, and 2b Studies

open access: yesInfectious Diseases and Therapy
Introduction Bepirovirsen is a novel antisense oligonucleotide in development for chronic hepatitis B virus (HBV) infection therapy. Understanding the impact that clinical characteristics may have on bepirovirsen exposure is important for determining ...
Amir S. Youssef   +4 more
doaj   +1 more source

Sharper bounds and new proofs of the exponential function with cotangent

open access: yesAIMS Mathematics, 2020
This paper provides a Páde interpolation based method for finding improved bounds for the exponential function with cotangent. In principle, it can recover many results in prevailing methods.
Xiangyang Wu   +3 more
doaj   +1 more source

Modeling and simulation of data communication networks using SARA [PDF]

open access: yes, 1985
The selection of an appropriate simulation language can have a profound impact on the success of a simulation study. The available options range from domain-specific simulation languages to general-purpose programming languages. These languages are often
Razouk, Rami R.
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Effect of Haptic Feedback on Pilot/Operator Performance During Flight Simulation

open access: yesApplied Sciences, 2020
Flying an unmanned aerial vehicle (UAV) is a challenging task, due to the absence of direct sensory information such as a view of surroundings, sound, vibrations, and motion. It is important to provide these sensory stimulations to an operator for better
Hassam Ahmed Malik   +3 more
doaj   +1 more source

Summary report of the Simulation Committee [PDF]

open access: yes, 1977
Topics discussed by the simulation committee included: (1) simulators and their uses; (2) atmospheric disturbance modeling requirements; (3) Status of simulators' capabilities for modeling disturbances; and (4) status of atmospheric disturbance models ...
Kurkowski, R. L.
core   +1 more source

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