Results 51 to 60 of about 586,656 (316)
Data‐Driven Stochastic Lie Transport Modeling of the 2D Euler Equations
Journal of Advances in Modeling Earth Systems, 2023 In this paper, we propose and assess several stochastic parametrizations for data‐driven modeling of the two‐dimensional Euler equations using coarse‐grid SPDEs.
Sagy R. Ephrati +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Profiling analytical combat models using extensible modeling and simulation framework (XMSF) principles [PDF]
, 2004 The Department of Defense (Dod) is engaged in warfighting and institutional transformation for the new millenium. In parallel, the DoD Modeling & Simulation (M&S) community is working to identify and adopt transformational technologies providing direct ...
Blais, Curtis L.
core
Turbulence models for simulation and modeling in textile engineering
, 2021 Turbulence accounts for most of the processes in textile engineering among other interdisciplinary fields. In this chapter, a comprehensive description of turbulent models and description of important terms and theories in modeling and simulation have ...
Nicholus Tayari Akankwasa +3 more
core +1 more source
Scientific Reports, 2021 Collaborative virtual environments are being used in various applications ranging from online games to complex team training scenarios. The key to the success of such environments is the ability of the participants to form a shared mental model of the ...
Nicholas Milef +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Delta3D: a complete open source game and simulation engine for building military training systems [PDF]
, 2006 Dela3D, the open source game and simulation engine built for military training, in continuing to be improved to meet the requirements of the military users.
McDowell, Perry +3 more
core
Cycle Network Model of Prostaglandin H Synthase-1
Pharmaceuticals, 2020 The kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was developed to investigate its complex network kinetics and non-steroidal anti-inflammatory drugs (NSAIDs) efficacy in different in vitro and in vivo conditions. To correctly describe the complex
Alexey Goltsov +3 more
doaj +1 more source
Simulation of econometric models [PDF]
Proceedings of the 6th conference on Winter simulation, 1973 The purposes of this tutorial are to present some fundamental properties of econometric model structures relevant to effective understanding of simulation procedures, and to describe the use of simulation software for analysis and forecasting.The fundamental concepts of model specification are developed formally to provide a logical foundation for ...
openaire +1 more source