Results 41 to 50 of about 5,296,026 (294)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Setting a Course for the Human Social Culture Behavior (HSCB) Modeling Standards Study Group [PDF]
, 2010 Documents include Paper and Presentation.Simulation Interoperability Standards Organization (SISO) SIW Conference PaperResearch and development efforts in modeling and simulation are increasingly focusing on the modeling of human societies, culture, and ...
Blais, Curtis
core +1 more source
CPT: Pharmacometrics & Systems PharmacologyThe purpose of the analysis was to evaluate if 10 mg naloxone, administered intramuscularly, could reverse or prevent opioid‐induced respiratory depression (OIRD), including OIRD associated with the administration of lethal doses of high‐potency opioids.
Tae Eun Yang +7 more
doaj +1 more source
Frontiers in Applied Mathematics and StatisticsA bioeconomic delay model is developed for an algae–fish ecosystem in which the time delay τ represents the lag required for nutrients released by fish decomposition to become bioavailable.
Saida Khiyar +3 more
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Effect of Haptic Feedback on Pilot/Operator Performance During Flight Simulation
Applied Sciences, 2020 Flying an unmanned aerial vehicle (UAV) is a challenging task, due to the absence of direct sensory information such as a view of surroundings, sound, vibrations, and motion. It is important to provide these sensory stimulations to an operator for better
Hassam Ahmed Malik +3 more
doaj +1 more source
Simulation of econometric models [PDF]
Proceedings of the 6th conference on Winter simulation, 1973 The purposes of this tutorial are to present some fundamental properties of econometric model structures relevant to effective understanding of simulation procedures, and to describe the use of simulation software for analysis and forecasting.The fundamental concepts of model specification are developed formally to provide a logical foundation for ...
openaire +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Sensors, 2021 A significant therapeutic challenge for people with disabilities is the development of verbal and echoic skills. Digital voice assistants (DVAs), such as Amazon’s Alexa, provide networked intelligence to billions of Internet-of-Things devices and have ...
Krzysztof J. Rechowicz +4 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source