Results 71 to 80 of about 1,873,107 (281)

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Anisotropic eddy-viscosity concept for strongly detached unsteady flows [PDF]

open access: yes, 2007
The accurate prediction of the flow physics around bodies at high Reynolds number is a challenge in aerodynamics nowadays. In the context of turbulent flow modeling, recent advances like large eddy simulation (LES) and hybrid methods [detached eddy ...
Bouhadji A.   +10 more
core   +2 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Interdomain I/O Optimization in Virtualized Sensor Networks

open access: yesSensors, 2018
In virtualized sensor networks, virtual machines (VMs) share the same hardware for sensing service consolidation and saving power. For those VMs that reside in the same hardware, frequent interdomain data transfers are invoked for data analytics, and ...
Congfeng Jiang   +6 more
doaj   +1 more source

Modeling techniques for quantum cascade lasers

open access: yes, 2014
Quantum cascade lasers are unipolar semiconductor lasers covering a wide range of the infrared and terahertz spectrum. Lasing action is achieved by using optical intersubband transitions between quantized states in specifically designed multiple-quantum ...
Jirauschek, Christian, Kubis, Tillmann
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

A tutorial for model‐based evaluation and translation of cardiovascular safety in preclinical trials

open access: yesCPT: Pharmacometrics & Systems Pharmacology
Assessment of drug‐induced effects on the cardiovascular (CV) system remains a critical component of the drug discovery process enabling refinement of the therapeutic index. Predicting potential drug‐related unintended CV effects in the preclinical stage
Victoria Kulesh   +6 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Dynamics of quantum information resources in two-flavor neutrino oscillations

open access: yesEuropean Physical Journal C: Particles and Fields
The burgeoning intersection of particle physics and quantum information science unveils significant connections, particularly in the context of neutrinos–fundamental particles that challenge our understanding of mass, mixing, and coherence at the quantum
K. El Bouzaidi   +4 more
doaj   +1 more source

The Effect of Integrating Travel Time

open access: yes, 2012
This contribution demonstrates the potential gain for the quality of results in a simulation of pedestrians when estimated remaining travel time is considered as a determining factor for the movement of simulated pedestrians. This is done twice: once for
A. Johansson   +16 more
core   +1 more source

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