Results 61 to 70 of about 176,482 (302)

Fuzzy local linear approximation-based sequential design [PDF]

open access: yes, 2014
When approximating complex high-fidelity black box simulators with surrogate models, the experimental design is often created sequentially. LOLA-Voronoi, a powerful state of the art method for sequential design combines an Exploitation and Exploration ...
Deschrijver, Dirk   +2 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Space station models, mockups and simulators [PDF]

open access: yes, 1985
Schematic outlines for space station models, mockups, and simulators are presented. The types of Boeing models, mockups, and simulators are given along with the classes and characteristics.
Miller, K. H., Osgood, A.
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Cross-level sensor network simulation with COOJA [PDF]

open access: yes, 2006
Simulators for wireless sensor networks are a valuable tool for system development. However, current simulators can only simulate a single level of a system at once.
Dunkels, Adam   +4 more
core   +4 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

The Racer’s Brain – How Domain Expertise is Reflected in the Neural Substrates of Driving

open access: yesFrontiers in Human Neuroscience, 2015
A fundamental question in human brain plasticity is how sensory, motor, and cognitive functions adapt in the process of skill acquisition extended over a period of many years.
Otto eLappi
doaj   +1 more source

Large-scale Reservoir Simulations on IBM Blue Gene/Q

open access: yes, 2016
This paper presents our work on simulation of large-scale reservoir models on IBM Blue Gene/Q and studying the scalability of our parallel reservoir simulators. An in-house black oil simulator has been implemented.
H Liu   +7 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Comparative performance of high-fidelity training models for flexible ureteroscopy: Are all models effective?

open access: yesIndian Journal of Urology, 2011
Objective: We performed a comparative study of high-fidelity training models for flexible ureteroscopy (URS). Our objective was to determine whether high-fidelity non-virtual reality (VR) models are as effective as the VR model in teaching flexible URS ...
Shashikant Mishra   +5 more
doaj   +1 more source

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