Results 61 to 70 of about 431,788 (272)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The ground state energy of the weakly interacting Bose gas at high density

open access: yes, 2008
We prove the Lee-Huang-Yang formula for the ground state energy of the 3D Bose gas with repulsive interactions described by the exponential function, in a simultaneous limit of weak coupling and high density.
Alessandro Giuliani   +8 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Simultaneous Approximation by Birkhoff Interpolators

open access: yesRocky Mountain Journal of Mathematics, 1998
The degree of simultaneous approximation by Birkhoff interpolators is given and the applications of this result to several concrete cases are provided.
Kacsó, Daniela P., Gonska, Heinz H.
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Approximation of derivatives by nonlinear operators

open access: yesJournal of Numerical Analysis and Approximation Theory, 2002
Two theorems on simultaneous approximation are obtained by using generalized convex operators.
Radu Păltănea
doaj   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Approximation of Bounded Continuous Functions by Linear Combinations of Phillips Operators

open access: yesDemonstratio Mathematica, 2014
We study the approximation properties of linear combinations of the so-called Phillips operators, which can be considered as genuine Szász-Mirakjan-Durrmeyer operators.
Tachev Gancho
doaj   +1 more source

On the Littlewood conjecture in simultaneous Diophantine approximation [PDF]

open access: yes, 2005
For any given real number $\alpha$ with bounded partial quotients, we construct explicitly continuum many real numbers $\beta$ with bounded partial quotients for which the pair $(\alpha, \beta)$ satisfies a strong form of the Littlewood conjecture.
Adamczewski, Boris, Bugeaud, Yann
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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