Results 61 to 70 of about 1,314,718 (282)

Simultaneous Approximation and Interpolation on Arakelian Sets

open access: yes, 2007
We extend results of P. M. Gauthier, W. Hengartner and A. A. Nersesyan on simultaneous approximation and interpolation on Arakelian sets.
Nikolai Nikolov, Peter Pflug
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Decision procedures for multiple auctions

open access: yes, 2002
This paper presents a decision theoretic framework that an autonomous agent can use to bid effectively across multiple, simultaneous auctions. Specifically our framework enables an agent to make rational decisions about purchasing multiple goods from a ...
Byde, A   +8 more
core   +2 more sources

Approximation of Bounded Continuous Functions by Linear Combinations of Phillips Operators

open access: yesDemonstratio Mathematica, 2014
We study the approximation properties of linear combinations of the so-called Phillips operators, which can be considered as genuine Szász-Mirakjan-Durrmeyer operators.
Tachev Gancho
doaj   +1 more source

Simultaneous Frobenius–Padé approximants

open access: yesJournal of Computational and Applied Mathematics, 2005
The authors consider simultaneous rational approximation with common denominator in the sense of the so called `German Polynomials' [cf. \textit{K. Mahler}, Perfect Systems, Comp. Math. 19, 95--166 (1968; Zbl 0168.31303)], constructed from formal power series \((f^1,\dots,f^d)\) in orthogonal polynomials \(\{P_k\}_{k\geq 0}\) with respect to a weight \(
Matos, Ana C., Van Iseghem, Jeannette
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Approximation of derivatives by nonlinear operators

open access: yesJournal of Numerical Analysis and Approximation Theory, 2002
Two theorems on simultaneous approximation are obtained by using generalized convex operators.
Radu Păltănea
doaj   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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