Results 61 to 70 of about 1,232,779 (280)

Approximation of Bounded Continuous Functions by Linear Combinations of Phillips Operators

Demonstratio Mathematica, 2014
We study the approximation properties of linear combinations of the so-called Phillips operators, which can be considered as genuine Szász-Mirakjan-Durrmeyer operators.
Tachev Gancho
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Best Approximation Of Bounded Functions By Continuous Functions

, 2015
[No abstract available]412135148Amir, Chebyshev centers and uniform convexity (1978) Pacific Journal of Mathematics, 77, pp. 1-6Amir, Deutsch, Approximation by certain subspaces in the Banach space of continuous vector-valued functions (1979) J.
Roversi M.S.M., ROVERSI, MSM
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Approximation of derivatives by nonlinear operators

Journal of Numerical Analysis and Approximation Theory, 2002
Two theorems on simultaneous approximation are obtained by using generalized convex operators.
Radu Păltănea
doaj   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Global Hypoellipticity and Simultaneous Approximability

Journal of Functional Analysis, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Himonas, A.Alexandrou, Petronilho, Gerson   +1 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

On exact rate of convergence of row sequences of multipoint Hermite-Padé approximants

Demonstratio Mathematica
In this article, we analyze a rate of attraction of poles of an approximated function to poles of incomplete multipoint Padé approximants and use it to derive a sharp bound on the geometric rate of convergence of multipoint Hermite-Padé approximants to a
Bosuwan Nattapong
doaj   +1 more source