Results 81 to 90 of about 51,771 (253)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
On simultaneous approximation for some modified Bernstein-type operators
International Journal of Mathematics and Mathematical Sciences, 2004 We study the simultaneous approximation for a certain variant of Bernstein-type operators.
Vijay Gupta, Nurhayat Ispir
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Approximation and geometric properties of some complex Bernstein-Stancu polynomials in compact disks
Journal of Numerical Analysis and Approximation Theory, 2007 In this paper, the order of simultaneous approximation, convergence results of the iterates and shape preserving properties, for complex Bernstein-Stancu polynomials (depending on one parameter) attached to analytic functions on compact disks are ...
Sorin G. Gal
doaj +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Simultaneous Approximation and Quasi-Interpolants
Journal of Approximation Theory, 1996 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Approximation by complex Stancu Beta operators of second kind in semidisks
Journal of Numerical Analysis and Approximation Theory, 2013 In this paper, the exact order of simultaneous approximation and Voronovskaja kind results with quantitative estimate for the complex Stancu Beta operator of second kind attached to analytic functions of exponential growth in semidisks of the right
Sorin G. Gal, Vijay Gupta
doaj +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source