Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Simultaneous Approximation by Birkhoff Interpolators
The degree of simultaneous approximation by Birkhoff interpolators is given and the applications of this result to several concrete cases are provided.
Kacsó, Daniela P., Gonska, Heinz H.
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Weighted Simultaneous Approximation of the Linear Combinations of Baskakov Operators
In this paper, the approximation property of the linear combinations of Baskakov operators is investigated by using a Jacobi weight function. Moreover, both the positive and inverse theorems for the weighted simultaneous approximation of the linear ...
Xiao-jun Tang, Xin-chang Wang, Hua Yi
doaj +1 more source
Simultaneous sparse approximation via greedy pursuit [PDF]
A simple sparse approximation problem requests an approximation of a given input signal as a linear combination of T elementary signals drawn from a large, linearly dependent collection.
Tropp, J. A. +2 more
core
Quantitative Khintchine in Simultaneous Approximation
In a ground-breaking work \cite{BY}, Beresnevich and Yang recently proved Khintchine's theorem in simultaneous Diophantine approximation for nondegenerate manifolds resolving a long-standing problem in the theory of Diophantine approximation.
Datta, Shreyasi
core
Necessary conditions for Pareto optimality in simultaneous Chebyshev best approximation [PDF]
Necessary conditions for Pareto optimality in constrained simultaneous Chebyshev best approximation, derived from an abstract characterization theory of Pareto optimality, are presented.
Yair Censor, Censor, Yair
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Best simultaneous approximation in normed linear spaces [PDF]
In this thesis we consider the problem of simultaneously approximating elements of a set B C X by a single element of a set K C X. This type of a problem arises when the element to be approximated is not known precisely but is known to belong to a set ...
Johnson, Solomon Nathan
core +1 more source

