Results 41 to 50 of about 15,025 (256)
The sinc–Galerkin method for solving Troesch’s problem
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Mohammad Zarebnia, M. Sajjadian
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This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
Designing the sinc neural networks to solve the fractional optimal control problem [PDF]
Sinc numerical methods are essential approaches for solving nonlinear problems. In this work, based on this method, the sinc neural networks (SNNs) are designed and applied to solve the fractional optimal control problem (FOCP) in the sense of the ...
R. Heydari Dastjerdi, G. Ahmadi
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SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang +17 more
wiley +1 more source
Approximation Techniques for Solving Linear Systems of Volterra Integro-Differential Equations
In this paper, a collocation method using sinc functions and Chebyshev wavelet method is implemented to solve linear systems of Volterra integro-differential equations.
Ahmad Issa +2 more
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Sinc interpolation of nonuniform samples [PDF]
It is well known that a bandlimited signal can be uniquely recovered from nonuniformly spaced samples under certain conditions on the nonuniform grid and provided that the average sampling rate meets or exceeds the Nyquist rate.
core +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source
Numerical solutions of one-dimensional non-linear parabolic equations using Sinc collocation method
We propose a numerical method for solving singularly perturbed one-dimensional non-linear parabolic problems. The equation converted to the nonlinear ordinary differential equation by discretization first in time then subsequently in each time level we ...
Jalil Rashidinia, Ali Barati
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UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
Linear Methods for Image Interpolation
We discuss linear methods for interpolation, including nearest neighbor, bilinear, bicubic, splines, and sinc interpolation. We focus on separable interpolation, so most of what is said applies to one-dimensional interpolation as well as N-dimensional ...
Pascal Getreuer
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