Results 51 to 60 of about 14,592 (227)

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

A Valid Dynamical Control on the Reverse Osmosis System Using the CESTAC Method

Mathematics, 2020
The aim of this study is to present a novel method to find the optimal solution of the reverse osmosis (RO) system. We apply the Sinc integration rule with single exponential (SE) and double exponential (DE) decays to find the approximate solution of the
Samad Noeiaghdam, Denis Sidorov, Alyona Zamyshlyaeva, Aleksandr Tynda, Aliona Dreglea   +4 more
doaj   +1 more source

HLA‐DR+ Schwann Cells Generate the Protumor Cancer‐Neuron‐Immune Niche in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
Hijacked and educated by HNSCC cells, HLA‐DR+ Schwann cells lost their normal neural‐related functions but acquired immunoregulatory phenotypes to promote CD4+ T cells transform into Tregs. HLA‐DR+ Schwann cells induced a macrophage subpopulation, Il1β.
Xiaoyan Meng, Zhonglong Liu, Shijian Zhang, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He   +7 more
wiley   +1 more source

Sinc-Galerkin method and a higher-order method for a 1D and 2D time-fractional diffusion equations

Boundary Value Problems
In this article, a new numerical algorithm for solving a 1-dimensional (1D) and 2-dimensional (2D) time-fractional diffusion equation is proposed. The Sinc-Galerkin scheme is considered for spatial discretization, and a higher-order finite difference ...
Man Luo, Da Xu, Xianmin Pan
doaj   +1 more source

Sinc-Approximations of Fractional Operators: A Computing Approach

Mathematics, 2015
We discuss a new approach to represent fractional operators by Sinc approximation using convolution integrals. A spin off of the convolution representation is an effective inverse Laplace transform.
Gerd Baumann, Frank Stenger
doaj   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

A “sinc-Galerkin” method of solution of boundary value problems [PDF]

Mathematics of Computation, 1979
This paper illustrates the application of a "Sinc-Galerkin" method to the approximate solution of linear and nonlinear second order ordinary differential equations, and to the approximate solution of some linear elliptic and parabolic partial differential equations in the plane.
openaire   +2 more sources

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

Advanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu, Jian Wan, Xue Zhang, Jiashuai Yan, Xi Chen, Xiaoqi Guan, Qianqian Ren, Tao Yang, Di Wu, Qingsong Guo, Yibing Guo, Yuhua Lu   +11 more
wiley   +1 more source

Numerical solution of singularly perturbed singular third order boundary value problems with nonclassical sinc method

Results in Applied Mathematics
In this paper, we employ a nonclassical sinc-collocation method to compute numerical solutions for singularly perturbed singular third-order boundary value problems prevalent in various scientific and engineering domains. Utilizing the sinc approximation
A. Alipanah, K. Mohammadi, R.M. Haji
doaj   +1 more source

Equivalent modeling for vibroacoustic analysis of diffuse acoustic excitation using uniformly distributed delta correlated excitation

Nihon Kikai Gakkai ronbunshu, 2014
In space engineering application, diffuse acoustic field is one of the critical design consideration of spacecraft structure. Diffuse acoustic field has equal probability of mutually uncorrelated plane waves from all incident angles over a half-space ...
Hiroki AKAGI, Shigemasa ANDO, Qinzhong SHI   +2 more
doaj   +1 more source