Results 121 to 130 of about 22,347 (256)

hnRNP A1 interacts with the genomic and subgenomic RNA promoters of Sindbis virus and is required for the synthesis of G and SG RNA

open access: yesJournal of Biomedical Science, 2010
Background Sindbis virus (SV) is the prototype of alphaviruses which are a group of widely distributed human and animal pathogens. Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an RNA-binding protein that shuttles between the nucleus and the ...
Stollar Victor   +4 more
doaj   +1 more source

Decreased Virulence of Ross River Virus Harboring a Mutation in the First Cleavage Site of Nonstructural Polyprotein Is Caused by a Novel Mechanism Leading to Increased Production of Interferon-Inducing RNAs

open access: yesmBio, 2018
Infection with Ross River virus (RRV) causes debilitating polyarthritis and arthralgia in individuals. Alphaviruses are highly sensitive to type I interferon (IFN). Mutations at the conserved P3 position of the cleavage site between nonstructural protein
Xiang Liu   +9 more
doaj   +1 more source

Bibliography on inactivation of viruses and rickettsiae by heat [PDF]

open access: yes
Inactivation of viruses and rickettsiae by heat ...
Homann, L. M., Watson, M. S.
core   +1 more source

Regulation of Sindbis virus RNA replication: uncleaved P123 and nsP4 function in minus-strand RNA synthesis, whereas cleaved products from P123 are required for efficient plus-strand RNA synthesis [PDF]

open access: yes, 1994
Nonstructural proteins of Sindbis virus, nsPl, nsP2, nsP3, and nsP4, as well as intermediate polyproteins, are produced from two precursor polyproteins, Pl23 and Pl234, by a proteolytic enzyme encoded in the C-terminal half of nsP2.
Shirako, Yukio, Strauss, James H.
core   +1 more source

RNAi Screening in Tumor Cells Identifies Artificial microRNAs That Improve Oncolytic Virus Replication

open access: yesPharmaceuticals
Background/Objectives: Oncolytic viruses infect and kill tumor cells while leaving normal cells unharmed. They are often attenuated through the reduction in their ability to antagonize antiviral defenses, leading to robust replication in tumor cells ...
Hannah Klemets   +9 more
doaj   +1 more source

Lysine-α-Oxidase in vitro Activity in Experiments on Models of Viruses Sindbis, Forest-Spring Encephalitis, Western Nile, Tyaginya and Dhori

open access: yesАнтибиотики и Химиотерапия, 2020
The antitumor effect of L-lysine-α-oxidase from the culture fluid of Trichoderma harzianum Rifai F-180 was investigated for the first time. The in vitro studies revealed Its high activity on a model of the forest-spring encephalitis virus and no activity
I. P. Smirnova   +2 more
doaj  

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