Results 101 to 110 of about 1,047,175 (209)

Prevalence and identification of arthropod-transmitted viruses in Kassala state, Eastern Sudan

Libyan Journal of Medicine, 2019
Vector-borne diseases are responsible for more than 20% of the infectious diseases worldwide. The prevalence of arboviruses transmit diseases to humans in Sudan has not been investigated.
Nahla Mohamed, Mamoun Magzoub, Rania El Hadi Mohamed, Fadilah Sfouq Aleanizy, Fulwah Y. Alqahtani, Bakri Y. M. Nour, Mubark M.S. Alkarsany   +6 more
doaj   +1 more source

Decreased Virulence of Ross River Virus Harboring a Mutation in the First Cleavage Site of Nonstructural Polyprotein Is Caused by a Novel Mechanism Leading to Increased Production of Interferon-Inducing RNAs

mBio, 2018
Infection with Ross River virus (RRV) causes debilitating polyarthritis and arthralgia in individuals. Alphaviruses are highly sensitive to type I interferon (IFN). Mutations at the conserved P3 position of the cleavage site between nonstructural protein
Xiang Liu, Margit Mutso, Age Utt, Anni Lepland, Lara J. Herrero, Adam Taylor, Jayaram Bettadapura, Penny A. Rudd, Andres Merits, Suresh Mahalingam   +9 more
doaj   +1 more source

In vitro and in vivo expression of foreign genes by transmissible gastroenteritis coronavirus-derived minigenomes [PDF]

, 2002
A helper-dependent expression system based on transmissible gastroenteritis coronavirus (TGEV) has been developed using a minigenome of 3·9 kb (M39).
Enjuanes, L., Plana-Duran, J., Reimann, I., Moormann, R.J.M., Sola, I., Plana Duran, J., Alonso, S., Izeta, A., Teifke, J.P., Teifke, Jens Peter, Reimann, Ilona, Balasch, M.   +11 more
core   +1 more source

hnRNP A1 interacts with the genomic and subgenomic RNA promoters of Sindbis virus and is required for the synthesis of G and SG RNA

Journal of Biomedical Science, 2010
Background Sindbis virus (SV) is the prototype of alphaviruses which are a group of widely distributed human and animal pathogens. Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an RNA-binding protein that shuttles between the nucleus and the ...
Stollar Victor, Adams Sandra, Lu Chi-Wei, Gui Hongxing, Li Mei-Ling   +4 more
doaj   +1 more source

Lysine-α-Oxidase in vitro Activity in Experiments on Models of Viruses Sindbis, Forest-Spring Encephalitis, Western Nile, Tyaginya and Dhori

Антибиотики и Химиотерапия, 2020
The antitumor effect of L-lysine-α-oxidase from the culture fluid of Trichoderma harzianum Rifai F-180 was investigated for the first time. The in vitro studies revealed Its high activity on a model of the forest-spring encephalitis virus and no activity
I. P. Smirnova, V. F. Larichev, Yu. A. Shneider   +2 more
doaj  

Insights into neutralization of animal viruses gained from study of influenza virus [PDF]

, 1991
It has long been known that the binding of antibodies to viruses can result in a loss of infectivity, or neutralization, but little is understood of the mechanism or mechanisms of this process.
Outlaw, Mark C., Dimmock, N. J.
core   +1 more source

Induction of programmed cell death in mammalian cells by isolates of Ross River virus [PDF]

, 2011
Arthritogenic alphaviruses, such as Ross River virus (RRV) are associated with worldwide outbreaks of human polyarthritis/arthralgia. The pathogenesis of RRV and other alphaviruses is poorly understood.
Back, Chelsea
core  

RNAi Screening in Tumor Cells Identifies Artificial microRNAs That Improve Oncolytic Virus Replication

Pharmaceuticals
Background/Objectives: Oncolytic viruses infect and kill tumor cells while leaving normal cells unharmed. They are often attenuated through the reduction in their ability to antagonize antiviral defenses, leading to robust replication in tumor cells ...
Hannah Klemets, Angelina Bardoul, Adrian Pelin, Ragunath Singaravelu, Meaghan Boileau, Theresa Falls, Julia Petryk, Marie-Claude Bourgeois-Daigneault, John C. Bell, Dominic G. Roy   +9 more
doaj   +1 more source

Sindbis virus interferes with dengue 4 virus replication and its potential transmission by Aedes albopictus

Parasites & Vectors, 2015
Background Mosquitoes transmit a number of arboviruses associated with disease outbreaks in humans and other animals. The majority of medically important arboviruses belong to three families: Togaviridae, Flaviviridae and Bunyaviridae. Several members of
Ephantus J Muturi, Jeffrey Bara
doaj   +1 more source

Effect of Ionic Strength on the Binding of Sindbis Virus to Chick Cells [PDF]

, 1974
Sindbis virus can adsorb to chicken embryo fibroblasts in two different ways. “Loosely” bound virus can be washed off the cell with buffers of ionic strength 0.2 or greater, whereas “tightly” bound virus remains attached under these conditions.
Strauss, Ellen G., Strauss, James H., Pierce, John S.   +2 more
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