Results 81 to 90 of about 13,197 (215)
ABSTRACT Introduction Black flies (Simuliidae) are globally distributed blood‐feeding arthropods and vectors of viral, bacterial, and parasitic pathogens to many animal species, including humans. We investigated the occurrence of selected vector‐borne pathogens in black flies in South Moravia, Czech Republic, and evaluated their possible role in the ...
Silvie Šikutová +10 more
wiley +1 more source
Enhanced susceptibility to bacterial infection in the days following an acute virus infection such as flu is a major clinical problem. Mouse models have provided major advances in understanding viral-bacterial superinfections, yet interactions of the ...
Laurent Boucontet +13 more
doaj +1 more source
RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao +7 more
wiley +1 more source
Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein [PDF]
bcl-2, the prototypic cellular antiapoptotic gene, decreases Sindbis virus replication and Sindbis virus-induced apoptosis in mouse brains, resulting in protection against lethal encephalitis.
Goldman, James E. +7 more
core +2 more sources
Amphibian Strategies Against Attacks by Flies: Host‐Specificity and Threats
Species interactions between Diptera flies and amphibians play a significant role in tropical ecosystems, but their ecology and evolution remain understudied. This review explores the costs flies impose on amphibians, such as pathogen transmission and disruption of communication systems, and highlights the evolutionary strategies employed by both ...
Leonardo Leite Ferraz de Campos +3 more
wiley +1 more source
Inhibition of Na+K+ATPase Activity in Membranes of Sindbis Virus-Infected Chick Cells [PDF]
Alterations in intracellular concentrations of Na+and K+in Sindbis virus-infected cells result largely from inhibition of ouabain-sensitive Na+K+ATPase (Na+pump) activity.
ULUG, EMIN T. +2 more
core +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
Longevity Studies of Sindbis Virus Infected Aedes Albopictus [PDF]
The persistent captive life cycle of a virus infected mosquito was examined. The model system used was Aedes albopictus and the Alphavirus, Sindbis virus. The adult life span of virus infected Ae. albopictus was compared to the life span of virus free Ae.
Kosova, Jonida
core +1 more source
Sindbis virus polyarthritis outbreak signalled by virus prevalence in the mosquito vectors [PDF]
Polyarthritis and rash caused by Sindbis virus (SINV), was first recognised in northern Europe about 50 years ago and is known as Ockelbo disease in Sweden and Pogosta disease in Finland.
Lundkvist, Åke, +38 more
core +1 more source
Alphaviruses are enveloped RNA viruses that contain several human pathogens. Here, the authors use block-based reconstruction method and provide a 3.5 Å cryo-EM structure of sindbis virus that identifies a conserved hydrophobic pocket near the viral ...
Lihong Chen +12 more
doaj +1 more source

