Results 81 to 90 of about 20,013 (221)

Phospholipid Synthesis in Sindbis Virus-Infected Cells [PDF]

Journal of Virology, 1970
We investigated the metabolic requirements for the decrease in phospholipid synthesis previously observed by Pfefferkorn and Hunter in primary cultures of chick embryo fibroblasts infected with Sindbis virus. The incorporation of 32 PO 4 into all classes of phospholipids was found to decline ...
M R, Waite, E R, Pfefferkorn
openaire   +2 more sources

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Imaging high-resolution structure of GFP-expressing neurons in neocortex in vivo [PDF]

, 2000
To detect subtle changes in neuronal morphology in response to changes in experience, one must image neurons at high resolution in vivo over time scales of minutes to days.
Burbach, B., Chen, B. E., Fox, K., Lendvai, B., Nimchinsky, E. A., Svoboda, K.   +5 more
core   +1 more source

Pepino Mosaic Virus: A Globally Important Tomato Pathogen and a Rising Model in Molecular Virology

Molecular Plant Pathology, Volume 27, Issue 1, January 2026.
Pepino mosaic virus (PepMV) is a globally important tomato pathogen causing fruit quality losses. It comprises multiple genetic types and spreads via seed and mechanical contact. Lacking resistant cultivars, management relies on cross‐protection. PepMV–tomato interactions provide a valuable model for studying virus–plant molecular mechanisms and ...
Jesús R. Úbeda, Livia Donaire, Cristina Alcaide, Miguel A. Aranda   +3 more
wiley   +1 more source

Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase [PDF]

, 1999
Successful trans-complementation of the defective Kunjin virus (KUN) RNA FLdGDD with a deletion of the RNA polymerase motif GDD in the NS5 gene by using a BHK cell line, repBHK that continuously produced a functionally active KUN replication complex (RC)
Adams S. C., Agapov E. V., Chu P. W., Chu P. W., Chu P. W., Coia G., Khromykh A. A., Mackenzie J. M., Mackenzie J. M., Novak J. E., Pryor M. J., Pryor M. J., Rees S., Schrader A. P., Tan B.-H., Westaway E. G., Westaway E. G.   +16 more
core   +1 more source

Biodiversity of Mosquitoes (Diptera: Culicidae) in High‐Risk Areas of Mosquito‐Borne Diseases in Southeastern Iran

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Bam County, owing its geographical location, is one of the high‐risk areas of mosquito‐borne diseases due to its ecological, socioeconomic, and topographic characteristics, but it seems that no study has been done on the species composition and biodiversity of mosquitoes in this area, so the present study aimed at determining mosquito ...
Saideh Yousefi, Nasrollah Saberi, Masoumeh Amin, Madineh Abbasi, Rajib Chowdhury   +4 more
wiley   +1 more source

A Model of Superinfection of Virus-Infected Zebrafish Larvae: Increased Susceptibility to Bacteria Associated With Neutrophil Death

Frontiers in Immunology, 2018
Enhanced susceptibility to bacterial infection in the days following an acute virus infection such as flu is a major clinical problem. Mouse models have provided major advances in understanding viral-bacterial superinfections, yet interactions of the ...
Laurent Boucontet, Laurent Boucontet, Gabriella Passoni, Gabriella Passoni, Valéry Thiry, Valéry Thiry, Ludovico Maggi, Ludovico Maggi, Philippe Herbomel, Philippe Herbomel, Jean-Pierre Levraud, Jean-Pierre Levraud, Emma Colucci-Guyon, Emma Colucci-Guyon   +13 more
doaj   +1 more source

Microassay for Sindbis virus and interferon activity [PDF]

Journal of Clinical Microbiology, 1983
A simple and rapid microplaque assay for Sindbis virus was developed which uses microtiter plates and overlay medium consisting of methylcellulose and specific antibody to Sindbis virus. Discrete plaque formation was consistently observed on baby hamster kidney (BHK-15) cells within 24 h. The assay was reproducible, quantitative, and had about the same
R E, Lloyd, D A, Weigent, G J, Stanton
openaire   +2 more sources

A Self‐Amplifying RNA Lipid Nanoparticle (saRNA‐LNP) Vaccine Provides Effective Protection Against Porcine Epidemic Diarrhea

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The development of vaccine platforms capable of inducing sustained, potent, and cost‐effective immunity remains a major challenge in veterinary vaccinology, particularly for coronaviruses, which are often associated with short‐lived vaccine‐induced protection.
Jinqi Shu, Han Zhang, Fang Wang, Hanyu Zhang, Xin Liu, Keshu Liu, Yinhe Zha, Wenqin Chai, Jianghui Yao, Yujun Lin, Chao Wu, Xiaomin Zhao, Jizong Li   +12 more
wiley   +1 more source

Regulation of autophagy and mTOR during Semliki Forest virus infection [PDF]

, 2012
Semliki Forest virus (SFV) infection causes dramatic changes to the infected cell. For example, synthesis of most cellular proteins shuts off within 4 hours.
Eng, Kai
core   +1 more source