Results 71 to 80 of about 13,197 (215)
“More” Artificial mRNAs: Beyond the Art of Nature
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui +3 more
wiley +1 more source
Sindbis virus expression vectors have been used successfully to express and silence genes of interest in vivo in several mosquito species, including Aedes aegypti, Ae. albopictus, Ae. triseriatus, Culex pipiens, Armigeres subalbatus and Anopheles gambiae.
L.L. Cheng +7 more
doaj
Sindbis virus (SINV) is a mosquito-borne alphavirus circulating globally. SINV outbreaks have been mainly reported in North-European countries. In Israel, SINV was detected in 6.3% of mosquito pools; however, SINV infection in humans has rarely been ...
Ravit Koren +6 more
doaj +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Comparison of Sindbis Virus-Induced Pathology in Mosquito and Vertebrate Cell Cultures [PDF]
We have compared Sindbis virus-induced cytopathology in vertebrate and mosquito (Aedes albopictus) cell cultures. It has been shown that vertebrate cells undergo apoptosis when infected by Sindbis virus and this was confirmed here using hamster cells ...
Karpf, Adam R., Brown, Dennis T.
core +1 more source
Langat Virus Biology and Infection
ABSTRACT Flaviviruses pose a major threat to global health and can cause severe disease in animals and humans. Among them, tick‐borne encephalitis virus (TBEV) and related members of the tick‐borne encephalitis (TBE) serocomplex are transmitted primarily by ticks and can lead to neurological disease, including encephalitis and death. Despite many years
Zinaida Klestova +3 more
wiley +1 more source
Mosquitoborne Viruses, Czech Republic, 2002
Specimens from residents (n = 497) of an area affected by the 2002 flood were examined serologically for mosquitoborne viruses. Antibodies were detected against Tahyna (16%), Sindbis (1%), and Batai (0.2%) viruses, but not West Nile virus. An examination
Zdenek Hubálek +7 more
doaj +1 more source
Abstract Background Equine encephalosis (EE) is caused by an Orbivirus from the family Sedoreoviridae and is thus similar to African horse sickness (AHS) and Bluetongue viruses (BTV). These viruses are transmitted by Culicoides midges. Equine encephalosis can infect horses, donkeys and zebras sub‐clinically while only horses develop clinical disease ...
Graeme Piketh +2 more
wiley +1 more source
Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions [PDF]
We have obtained a vaccinia virus recombinant which contains a complete cDNA copy of the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome.
Rice, Charles M. +3 more
core
Sindbis viruksen paluu : kahden uuden Sindbis viruskannan eristäminen ihmisen seeruminäytteestä ja hyttysnäytteestä vuodelta 2018 [PDF]
Sindbis-virus kuuluu alfavirusten sukuun, ja sitä tavataan ympäri maapalloa. Sindbis-virus leviää hyttysten ja lintujen välityksellä. Lintu- (Culex) ja elohyttysten (Culiseta) on havaittu levittävän Sindbis-virusta.
Suvanto, Maija Tellervo
core

