Results 91 to 100 of about 20,013 (221)

Isolation and Pathogenicity of a Getah Virus With a Novel Deletion in the 3′ UTR

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The spread of Getah virus (GETV) in China has become increasingly severe due to long‐term neglect and the lack of vaccines, posing a threat to animal safety and public health. In this study, we isolated and identified a novel GETV strain, designated GETV‐CX7.
Yawei Sun   +11 more
wiley   +1 more source

Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus. [PDF]

open access: yes, 1990
Intracellular events in the synthesis, glycosylation, and transport of the lymphocytic choriomeningitis virus (LCMV) glycoproteins have been examined. We have shown by N-glycanase digestion that LCMV strain Arm-4 bears five oligosaccharides on GP-1 and ...
Buchmeier, MJ   +3 more
core  

Development of the nanobody display technology to target lentiviral vectors to antigen-presenting cells [PDF]

open access: yes, 2012
Lentiviral vectors (LVs) provide unique opportunities for the development of immunotherapeutic strategies, as they transduce a variety of cells in situ, including antigen-presenting cells (APCs). Engineering LVs to specifically transduce APCs is required
Breckpot, Karine   +10 more
core   +1 more source

Proteolytic dissection of Sindbis virus core protein [PDF]

open access: yesJournal of Virology, 1990
Mild trypsin treatment of the Sindbis virus nucleocapsid protein yields a fragment with a molecular mass of approximately 18.5 kilodaltons with its N terminus at residue 105. The fragment, which is stable to further digestion, appears by gel exclusion chromatography to be monomeric.
R K, Strong, S C, Harrison
openaire   +2 more sources

Establishment of a New Real-Time Molecular Assay for the Detection of Babanki Virus in Africa

open access: yesViruses
Babanki virus is a subtype of the Sindbis virus, a widespread arthropod-borne alphavirus circulating in Eurasia, Africa, and Oceania. Characterized by rashes and arthritis, clinical infections due to Sindbis were mainly reported in Africa, Australia ...
Martin Faye   +10 more
doaj   +1 more source

Implication for alphavirus host-cell entry and assembly indicated by a 3.5Å resolution cryo-EM structure

open access: yesNature Communications, 2018
Alphaviruses are enveloped RNA viruses that contain several human pathogens. Here, the authors use block-based reconstruction method and provide a 3.5 Å cryo-EM structure of sindbis virus that identifies a conserved hydrophobic pocket near the viral ...
Lihong Chen   +12 more
doaj   +1 more source

A Viral mRNA Motif at the 3′-Untranslated Region that Confers Translatability in a Cell-Specific Manner. Implications for Virus Evolution [PDF]

open access: yes, 2016
Sindbis virus (SINV) mRNAs contain several motifs that participate in the regulation of their translation. We have discovered a motif at the 3′ untranslated region (UTR) of viral mRNAs, constituted by three repeated sequences, which is involved in the ...
Carrasco, Luis   +2 more
core   +2 more sources

Automated Label‐Free Assay for Viral Detection and Inhibitor Screening via Biomembrane‐Functionalized Microelectrode Arrays

open access: yesAdvanced Materials, Volume 37, Issue 51, December 23, 2025.
A bioelectronic sensor integrating 2D cell membranes with organic microelectrode arrays enables detection of SARS‐CoV‐2 fusion pathways. Natively‐expressed viral receptors promote monitoring of viral entry and screening of antibody‐based inhibitors.
Zixuan Lu   +17 more
wiley   +1 more source

Mosquitoborne Sindbis Virus Infection and Long-Term Illness

open access: yesEmerging Infectious Diseases, 2018
An unexpected human outbreak of the mosquitoborne Sindbis virus occurred in a previously nonendemic area of Sweden. At follow-up, 6–8 months after infection, 39% of patients had chronic arthralgia that affected their daily activities.
Åsa Gylfe   +7 more
doaj   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

open access: yesAdvanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu   +20 more
wiley   +1 more source

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