Results 111 to 120 of about 20,013 (221)

Prevalence and identification of arthropod-transmitted viruses in Kassala state, Eastern Sudan

Libyan Journal of Medicine, 2019
Vector-borne diseases are responsible for more than 20% of the infectious diseases worldwide. The prevalence of arboviruses transmit diseases to humans in Sudan has not been investigated.
Nahla Mohamed, Mamoun Magzoub, Rania El Hadi Mohamed, Fadilah Sfouq Aleanizy, Fulwah Y. Alqahtani, Bakri Y. M. Nour, Mubark M.S. Alkarsany   +6 more
doaj   +1 more source

Decreased Virulence of Ross River Virus Harboring a Mutation in the First Cleavage Site of Nonstructural Polyprotein Is Caused by a Novel Mechanism Leading to Increased Production of Interferon-Inducing RNAs

mBio, 2018
Infection with Ross River virus (RRV) causes debilitating polyarthritis and arthralgia in individuals. Alphaviruses are highly sensitive to type I interferon (IFN). Mutations at the conserved P3 position of the cleavage site between nonstructural protein
Xiang Liu, Margit Mutso, Age Utt, Anni Lepland, Lara J. Herrero, Adam Taylor, Jayaram Bettadapura, Penny A. Rudd, Andres Merits, Suresh Mahalingam   +9 more
doaj   +1 more source

Statistical analysis of sizes and shapes of virus capsids and their resulting elastic properties

, 2013
From the analysis of sizes of approximately 130 small icosahedral viruses we find that there is a typical structural capsid protein, having a mean diameter of 5 nm and a mean thickness of 3 nm, with more than two thirds of the analyzed capsid proteins ...
Bozic, Anze Losdorfer, Podgornik, Rudolf, Siber, Antonio   +2 more
core   +1 more source

Viruses and the cellular RNA decay machinery. [PDF]

, 2010
The ability to control cellular and viral gene expression, either globally or selectively, is central to a successful viral infection, and it is also crucial for the host to respond and eradicate pathogens.
Gaglia, Marta, Glaunsinger, Britt
core   +1 more source

Advances in dissecting mosquito innate immune responses to arbovirus infection [PDF]

, 2009
Arthropod-borne viruses – arboviruses – are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control ...
A. A. Nash, A. Kohl, Aliyari, Alphey, Barillas-Mury, Barillas-Mury, Best, Blair, Blitvich, Borucki, Bowers, Bowie, Campbell, Campbell, Caudy, Caudy, Christophides, Christophides, Cirimotich, Condreay, Deddouche, Deo, Ding, Dostert, Ferrandon, Fragkoudis, G. Attarzadeh-Yazdi, Galiana-Arnoux, Garcia, Garcia, Garmashova, Geiss, Gillies, Gillies, Girard, GIRARD, Gordon, Gordon, Gould, Halstead, Hedges, Hedges, Hirai, Holt, J. K. Fazakerley, Jiravanichpaisal, Kang, Karpf, Kemp, Kuno, Kyle, Landeg, Lemaitre, Li, Li, Lin, McMeniman, Medeiros, Mims, Molnar, Newton, Obbard, Olson, Osta, Papanayotou, Parikh, Powers, R. Fragkoudis, Randall, Robalino, Robalino, Sabatier, Saleh, Sanchez-Vargas, Sanchez-Vargas, Sanders, Scholthof, Shelly, Sim, Sim, Soldan, Tortosa, Travanty, van Rij, van Rij, Voinnet, Wang, Waterhouse, Weaver, Weaver, Weaver, Weaver, Whitten, Xi, Xie, Yoneyama, Zambon, Zelivianski   +97 more
core   +1 more source

Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. [PDF]

, 2016
The host responds to virus infection by activating type I interferon (IFN) signaling leading to expression of IFN-stimulated genes (ISGs). Dysregulation of the IFN response results in inflammatory diseases and chronic infections.
Bozzacco, Leonia, Breton, Gaëlle, Hoffmann, Hans-Heinrich, Li, Melody MH, Loschko, Jakob, MacDonald, Margaret R, Monette, Sébastien, Rice, Charles M, Xiao, Jing W   +8 more
core  

Sequence coding for the alphavirus nonstructural proteins is interrupted by an opal termination codon [PDF]

, 1983
We have obtained the nucleotide sequence of the genomic RNAs of two alphaviruses, Sindbis virus and Middelburg virus, over an extensive region encoding the nonstructural (replicase) proteins.
Rice, Charles M., Strauss, Ellen G., Strauss, James H.   +2 more
core  

Lysine-α-Oxidase in vitro Activity in Experiments on Models of Viruses Sindbis, Forest-Spring Encephalitis, Western Nile, Tyaginya and Dhori

Антибиотики и Химиотерапия, 2020
The antitumor effect of L-lysine-α-oxidase from the culture fluid of Trichoderma harzianum Rifai F-180 was investigated for the first time. The in vitro studies revealed Its high activity on a model of the forest-spring encephalitis virus and no activity
I. P. Smirnova, V. F. Larichev, Yu. A. Shneider   +2 more
doaj  

Serologic survey of wild boars for mosquito-borne viruses in South Moravia (Czech Republic)

Veterinární Medicína, 2008
A serosurvey for mosquito-borne viruses was carried out in 93 wild boars (Sus scrofa), using a plaque-reduction neutralization microtest with Vero cells.
J. Halouzka, Z. Juricova, J. Jankova, Z. Hubalek   +3 more
doaj   +1 more source

RNAi Screening in Tumor Cells Identifies Artificial microRNAs That Improve Oncolytic Virus Replication

Pharmaceuticals
Background/Objectives: Oncolytic viruses infect and kill tumor cells while leaving normal cells unharmed. They are often attenuated through the reduction in their ability to antagonize antiviral defenses, leading to robust replication in tumor cells ...
Hannah Klemets, Angelina Bardoul, Adrian Pelin, Ragunath Singaravelu, Meaghan Boileau, Theresa Falls, Julia Petryk, Marie-Claude Bourgeois-Daigneault, John C. Bell, Dominic G. Roy   +9 more
doaj   +1 more source