Results 61 to 70 of about 13,177 (216)
BioTechniques, 1996 Recombinant alphaviruses have been used as vehicles for delivery and expression of heterologous genes in mammalian, avian and insect cell lines. We have used a Sindbis replicon virus (Sinreplac) able to express the E.
J. Corsini +4 more
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“More” Artificial mRNAs: Beyond the Art of Nature
Advanced Science, Volume 13, Issue 20, 9 April 2026.Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui +3 more
wiley +1 more source
Retrovirology, 2010 Background The ability to efficiently and selectively target gene delivery vectors to specific cell types in vitro and in vivo remains one of the formidable challenges in gene therapy.
Marino Michael P +5 more
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Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
Advanced Science, Volume 13, Issue 14, 9 March 2026.This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Journal of Insect Science, 2001 Sindbis virus expression vectors have been used successfully to express and silence genes of interest in vivo in several mosquito species, including Aedes aegypti, Ae. albopictus, Ae. triseriatus, Culex pipiens, Armigeres subalbatus and Anopheles gambiae.
L.L. Cheng +7 more
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Viruses, 2019 Sindbis virus (SINV) is a mosquito-borne alphavirus circulating globally. SINV outbreaks have been mainly reported in North-European countries. In Israel, SINV was detected in 6.3% of mosquito pools; however, SINV infection in humans has rarely been ...
Ravit Koren +6 more
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Langat Virus Biology and Infection
Reviews in Medical Virology, Volume 36, Issue 2, March 2026.ABSTRACT Flaviviruses pose a major threat to global health and can cause severe disease in animals and humans. Among them, tick‐borne encephalitis virus (TBEV) and related members of the tick‐borne encephalitis (TBE) serocomplex are transmitted primarily by ticks and can lead to neurological disease, including encephalitis and death. Despite many years
Zinaida Klestova +3 more
wiley +1 more source
Aura Virus Is a New World Representative of Sindbis-like Viruses
, 1995 Aura virus is an alphavirus present in Brazil and Argentina that is serologically related to Sindbis virus (present throughout the Old World) and to Western equine encephalitis (WEE) virus (present in the Americas). We have previously shown that WEE is a
Strauss, Ellen G. +2 more
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Equine Veterinary Journal, Volume 58, Issue 2, Page 434-443, March 2026.Abstract Background Equine encephalosis (EE) is caused by an Orbivirus from the family Sedoreoviridae and is thus similar to African horse sickness (AHS) and Bluetongue viruses (BTV). These viruses are transmitted by Culicoides midges. Equine encephalosis can infect horses, donkeys and zebras sub‐clinically while only horses develop clinical disease ...
Graeme Piketh +2 more
wiley +1 more source
Mosquitoborne Viruses, Czech Republic, 2002
Emerging Infectious Diseases, 2005 Specimens from residents (n = 497) of an area affected by the 2002 flood were examined serologically for mosquitoborne viruses. Antibodies were detected against Tahyna (16%), Sindbis (1%), and Batai (0.2%) viruses, but not West Nile virus. An examination
Zdenek Hubálek +7 more
doaj +1 more source