Results 61 to 70 of about 20,013 (221)
Mutagenesis of the conserved 51-nucleotide region of Sindbis virus [PDF]
, 1990 We have constructed 25 site-specific mutations in a domain of 51 nucleotides in Sindbis virus that is highly conserved among all alphaviruses sequenced to date.
Niesters, Hubert G. M. +1 more
core
Langat Virus Biology and Infection
Reviews in Medical Virology, Volume 36, Issue 2, March 2026.ABSTRACT Flaviviruses pose a major threat to global health and can cause severe disease in animals and humans. Among them, tick‐borne encephalitis virus (TBEV) and related members of the tick‐borne encephalitis (TBE) serocomplex are transmitted primarily by ticks and can lead to neurological disease, including encephalitis and death. Despite many years
Zinaida Klestova +3 more
wiley +1 more source
BioTechniques, 1996 Recombinant alphaviruses have been used as vehicles for delivery and expression of heterologous genes in mammalian, avian and insect cell lines. We have used a Sindbis replicon virus (Sinreplac) able to express the E.
J. Corsini +4 more
doaj +1 more source
Site-directed mutagenesis of the proposed catalytic amino acids of the Sindbis virus capsid protein autoprotease [PDF]
, 1990 The structural proteins of Sindbis virus are translated as a polyprotein precursor that is cleaved upon translation. The capsid protein is postulated to be a serine protease that releases itself from the N terminus of the nascent polyprotein by ...
Hahn, Chang S., Strauss, James H.
core
Equine Veterinary Journal, Volume 58, Issue 2, Page 434-443, March 2026.Abstract Background Equine encephalosis (EE) is caused by an Orbivirus from the family Sedoreoviridae and is thus similar to African horse sickness (AHS) and Bluetongue viruses (BTV). These viruses are transmitted by Culicoides midges. Equine encephalosis can infect horses, donkeys and zebras sub‐clinically while only horses develop clinical disease ...
Graeme Piketh +2 more
wiley +1 more source
Retrovirology, 2010 Background The ability to efficiently and selectively target gene delivery vectors to specific cell types in vitro and in vivo remains one of the formidable challenges in gene therapy.
Marino Michael P +5 more
doaj +1 more source
Defined mutations in the 5' nontranslated sequence of Sindbis virus RNA [PDF]
, 1990 We have constructed 24 deletion mutants which contain deletions of from 1 to 15 nucleotides in the 5' nontranslated region of Sindbis virus RNA and tested the effect of these mutations on virus replication.
Niesters, Hubert G. M. +1 more
core +2 more sources
Membrane-Mediated Alterations of Intracellular Na+ and K+ in Lytic-Virus-Infected and Retrovirus-Transformed Cells [PDF]
Infection of chick-embryo fibroblasts and other ceils by certain animal viruses results in alterations in the intracellular concentrations of Na + and K +.
Bose, Henry R. +2 more
core +1 more source
Mapping of RNA- temperature-sensitive mutants of Sindbis virus: assignment of complementation groups A, B, and G to nonstructural proteins [PDF]
, 1989 Four complementation groups of temperature-sensitive (ts) mutants of Sindbis virus that fail to make RNA at the nonpermissive temperature are known, and we have previously shown that group F mutants have defects in nsP4.
Hahn, Young S. +2 more
core +1 more source
Why enveloped viruses need cores -- the contribution of a nucleocapsid core to viral budding
, 2017 During the alphavirus lifecycle, a nucleocapsid core buds through the cell membrane to acquire an outer envelope of lipid membrane and viral glycoproteins. However, the presence of a nucleocapsid core is not required for assembly of infectious particles.
Hagan, Michael F. +2 more
core +1 more source