Results 61 to 70 of about 1,047,175 (209)

Structural Modifications of Nonsteroidal Anti‐Inflammatory Drugs (NSAIDs): New Horizons in Antimicrobial Drug Discovery

open access: yesArchiv der Pharmazie, Volume 359, Issue 8, August 2026.
This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan   +2 more
wiley   +1 more source

Longevity Studies of Sindbis Virus Infected Aedes Albopictus [PDF]

open access: yes, 2003
The persistent captive life cycle of a virus infected mosquito was examined. The model system used was Aedes albopictus and the Alphavirus, Sindbis virus. The adult life span of virus infected Ae. albopictus was compared to the life span of virus free Ae.
Kosova, Jonida
core   +1 more source

Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]

open access: yes, 1987
Intraperitoneal infection with the avirulent A7(74) strain of the alphavirus Semliki Forest virus (SFV) induces an immune mediated demyelinating encephalomyelitis.
Fazakerley, J K, Webb, H E
core  

Innate immunity shapes the persistent transmission of plant viruses by insect vectors

open access: yesNew Plant Protection, Volume 3, Issue 2, June 2026.
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley   +1 more source

Efficiency of Transduction by Recombinant Sindbis Replicon Virus Varies Among Cell Lines, Including Mosquito Cells and Rat Sensory Neurons

open access: yesBioTechniques, 1996
Recombinant alphaviruses have been used as vehicles for delivery and expression of heterologous genes in mammalian, avian and insect cell lines. We have used a Sindbis replicon virus (Sinreplac) able to express the E.
J. Corsini   +4 more
doaj   +1 more source

mRNA Lipid Nanoparticles for Cell Engineering in Vivo and in Vitro: Current Applications and Future Directions

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Schematic diagram of mRNA‐lipid nanoparticles (mRNA‐LNP) and its functional mechanisms, applications, and challenges in cell engineering. This figure details the structural composition of mRNA‐LNPs and the delivery strategy, highlighting three core challenges.
Lina Li   +9 more
wiley   +1 more source

Cell-specific targeting of lentiviral vectors mediated by fusion proteins derived from Sindbis virus, vesicular stomatitis virus, or avian sarcoma/leukosis virus

open access: yesRetrovirology, 2010
Background The ability to efficiently and selectively target gene delivery vectors to specific cell types in vitro and in vivo remains one of the formidable challenges in gene therapy.
Marino Michael P   +5 more
doaj   +1 more source

Sustainable Nanocellulose‐Based Materials for Environmental Remediation: Structure–Function Relationships and Applications

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Environmental pollution across water, air, and soil systems poses escalating threats to human health and ecosystem stability, driven by heavy metals, persistent organic pollutants, particulate matter (PM), bioaerosols, and toxic gases. Conventional remediation technologies often suffer from limited selectivity, insufficient efficiency, and the
Junjie Qi   +6 more
wiley   +1 more source

Characterization of an endogenous gene expressed in Aedes aegypti using an orally infectious recombinant sindbis virus

open access: yesJournal of Insect Science, 2001
Sindbis virus expression vectors have been used successfully to express and silence genes of interest in vivo in several mosquito species, including Aedes aegypti, Ae. albopictus, Ae. triseriatus, Culex pipiens, Armigeres subalbatus and Anopheles gambiae.
L.L. Cheng   +7 more
doaj  

Placement of the Structural Proteins in Sindbis Virus [PDF]

open access: yesJournal of Virology, 2002
ABSTRACT The structure of the lipid-enveloped Sindbis virus has been determined by fitting atomic resolution crystallographic structures of component proteins into an 11-Å resolution cryoelectron microscopy map. The virus has T =4 quasisymmetry elements that are accurately maintained between the external ...
Wei, Zhang   +5 more
openaire   +2 more sources

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