Results 61 to 70 of about 13,197 (215)
Enzymatic Iodination of Sindbis Virus Proteins [PDF]
Sindbis virus was iodinated by using the enzyme lactoperoxidase, an iodination technique which labels only surface proteins. By this technique, the two viral glycoproteins are labeled, and the internal viral protein is not. The two glycoproteins are iodinated to strikingly different extents. This difference in susceptibility to iodination apparently is
B M, Sefton, G G, Wickus, B W, Burge
openaire +2 more sources
Schematic diagram of mRNA‐lipid nanoparticles (mRNA‐LNP) and its functional mechanisms, applications, and challenges in cell engineering. This figure details the structural composition of mRNA‐LNPs and the delivery strategy, highlighting three core challenges.
Lina Li +9 more
wiley +1 more source
Molecular characterization of a receptor for the Togavirus Sindbis virus [PDF]
The first step in any virus entry process is binding to the plasma membrane of the host cell. The nature of this obligatory step depends upon both the viral and cellular components and may be quite diverse among viruses. The entry of Sindbis virus into a
Wang, Kang-Sheng
core +1 more source
ABSTRACT Environmental pollution across water, air, and soil systems poses escalating threats to human health and ecosystem stability, driven by heavy metals, persistent organic pollutants, particulate matter (PM), bioaerosols, and toxic gases. Conventional remediation technologies often suffer from limited selectivity, insufficient efficiency, and the
Junjie Qi +6 more
wiley +1 more source
Recombinant alphaviruses have been used as vehicles for delivery and expression of heterologous genes in mammalian, avian and insect cell lines. We have used a Sindbis replicon virus (Sinreplac) able to express the E.
J. Corsini +4 more
doaj +1 more source
Vector‐borne diseases‐knowledge maps
Abstract This scientific report provides a structured overview of the main characteristics of 25 selected vector‐borne diseases (VBDs) of potential relevance for the EU, including 12 diseases listed under the Animal Health Law (AHL) and 13 non‐listed diseases.
European Food Safety Authority (EFSA) +7 more
wiley +1 more source
Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]
Intraperitoneal infection with the avirulent A7(74) strain of the alphavirus Semliki Forest virus (SFV) induces an immune mediated demyelinating encephalomyelitis.
Fazakerley, J K, Webb, H E
core
Background The ability to efficiently and selectively target gene delivery vectors to specific cell types in vitro and in vivo remains one of the formidable challenges in gene therapy.
Marino Michael P +5 more
doaj +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Investigation of the Role of the E2 Endodomain in Sindbis Virus Assembly [PDF]
Sindbis virus (SV) is the prototype member of the alphavirus genus belonging to the family Togaviridae. SV is a mosquito-borne virus that can be transmitted to both humans and other animals via mosquito bloodmeal.
West, John
core

