Results 41 to 50 of about 13,197 (215)
The metabolic resources crucial for viral replication are provided by the host. Details of the mechanisms by which viruses interact with host metabolism, altering and recruiting high free-energy molecules for their own replication, remain unknown ...
Leandro Silva da Costa +3 more
doaj +1 more source
Homologous Interference Induced by Sindbis Virus [PDF]
Homologous interference during Sindbis virus infection has been investigated. Prior infection of either chicken embryo fibroblast or BHK 21 cell cultures results in reduced yields of progeny virions of the superinfecting genotype.
R E, Johnston, K, Wan, H R, Bose
openaire +2 more sources
We have recently demonstrated an essential role of the domain of 145-150 amino acid in the E2 glycoprotein of Sindbis virus in the interaction with cellular heparan sulfate (HS) and in the infection of mouse embryonic fibroblasts (MEF) cells.
Zhu Wuyang +4 more
doaj +1 more source
Aura Virus Is a New World Representative of Sindbis-like Viruses [PDF]
Aura virus is an alphavirus present in Brazil and Argentina that is serologically related to Sindbis virus (present throughout the Old World) and to Western equine encephalitis (WEE) virus (present in the Americas). We have previously shown that WEE is a
Strauss, Ellen G. +2 more
core +1 more source
Arboviruses including alphavirus are responsible for most emerging infectious diseases worldwide. Recent outbreaks of chikungunya virus serve as a stark reminder to their pathogenic potential.
Mohanraj Manangeeswaran +4 more
doaj +1 more source
Microassay for Sindbis virus and interferon activity [PDF]
A simple and rapid microplaque assay for Sindbis virus was developed which uses microtiter plates and overlay medium consisting of methylcellulose and specific antibody to Sindbis virus. Discrete plaque formation was consistently observed on baby hamster kidney (BHK-15) cells within 24 h. The assay was reproducible, quantitative, and had about the same
R E, Lloyd, D A, Weigent, G J, Stanton
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Epidemiology of Sindbis virus [PDF]
Data representing the end-point titers of the samples tested in the neutralization antibody assay.he datasets represent the following: 1. Data representing the end-point titers of the samples tested in the neutralization antibody assay. 2.
Kgothatso Meno (12094847)
core +1 more source
Genetic determinants of Sindbis virus neuroinvasiveness [PDF]
After peripheral inoculation of mice, Sindbis virus replicates in a variety of tissues, leading to viremia. In some cases, the virus can enter the central nervous system (CNS) and cause lethal encephalitis. The outcome of infection is age and virus strain dependent.
J, Dubuisson +4 more
openaire +2 more sources
The impact of RNA viruses on the posttranscriptional regulation of cellular gene expression is unclear. Sindbis virus causes a dramatic relocalization of the cellular HuR protein from the nucleus to the cytoplasm in infected cells.
Michael D. Barnhart +4 more
doaj +1 more source
Recombination between Sindbis virus RNAs [PDF]
The genome (49S RNA) of Sindbis virus is a positive-strand RNA of 11.7 kb that consists of two domains. The 5' two-thirds of the RNA codes for the proteins required for replication and transcription of the RNA. The 3' one-third codes for the structural proteins.
B G, Weiss, S, Schlesinger
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