Results 41 to 50 of about 20,013 (221)
Sindbis Virus with a Tricomponent Genome [PDF]
Journal of Virology, 2005 ABSTRACT We established a system for propagation of Sindbis virus (SIN)-based replicons in tissue culture in the form of a tricomponent genome virus. Three RNA fragments containing complementing genetic information required for virus replication are packaged into separate viral particles, and each cell produces at least 1,000 packaged ...
Rafik, Fayzulin +4 more
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Antiviral activity of glycopeptide antibiotics derivates against Sindbis virus
International Journal of Infectious DiseasesIntroduction: Thousands of human infective viruses spread worldwide, yet protective measures exist for only a fraction, with internationally accepted vaccines available for an even smaller subset.
Ms Krisztina Leiner +8 more
doaj +1 more source
The interferon-induced exonuclease ISG20 exerts antiviral activity through upregulation of type I interferon response proteins [PDF]
, 2018 The host immune responses to infection lead to the production of type I interferon (IFN), and the upregulation of interferon-stimulated genes (ISGs) reduces virus replication and virus dissemination within a host.
Diamond, Michael S +6 more
core +2 more sources
Biosynthesis of the Sindbis Virus Carbohydrates [PDF]
Journal of Virology, 1973 The sequence in which sugars are added to the Sindbis virus glycoproteins was studied. Infected cells contain three glycosylated virus-specific proteins: the two virion glycoproteins and the immediate precursor to the smaller virion glycoprotein. Larger Sindbis-specific proteins are not glycosylated.
B M, Sefton, B W, Burge
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Cell Reports, 2013 The impact of RNA viruses on the posttranscriptional regulation of cellular gene expression is unclear. Sindbis virus causes a dramatic relocalization of the cellular HuR protein from the nucleus to the cytoplasm in infected cells.
Michael D. Barnhart +4 more
doaj +1 more source
Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges [PDF]
, 2014 Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal health, yet effective control measures have proven difficult to implement, and novel means of controlling their replication in arthropod vectors, such as mosquitoes, are
Dietrich, Isabelle +3 more
core +1 more source
Research on basis of reverse genetics system of a Sindbis-like virus XJ-160
Virology Journal, 2011 As a Sindbis-like virus (SINLV), XJ-160 virus was isolated from a pooled sample of Anopheles mosquitoes collected in Xinjiang, China, in 1990. Recombinant plasmid pBR-XJ160 is an infectious full-length cDNA clone of XJ-160 virus, from which rescued virus
Wu-yang Zhu, Guo-dong Liang
doaj +1 more source
Vaccines, 2021 Crimean–Congo hemorrhagic fever virus (CCHFV) infrequently causes hemorrhagic fever in humans with a case fatality rate of 30%. Currently, there is neither an internationally approved antiviral drug nor a vaccine against the virus.
Thomas Tipih +2 more
doaj +1 more source
Autophagy induction regulates influenza virus replication in a time-dependent manner [PDF]
, 2017 Autophagy plays a key role in host defence responses against microbial infections by promoting degradation of pathogens and participating in acquired immunity.
Abdoli, Asghar +12 more
core +1 more source
Agglutination of Sindbis Virus and of Cells Infected with Sindbis Virus by Plant Lectins [PDF]
Journal of Virology, 1973 We have examined the agglutination of Sindbis virus and of chick and hamster cells infected with Sindbis virus by two of the plant lectins, concanavalin A and Ricinus communis agglutinin. Both lectins agglutinate the virus by binding to the polysaccharide chains of the envelope glycoproteins.
Birdwell, Charles R., Strauss, James H.
openaire +2 more sources