Results 41 to 50 of about 13,197 (215)

Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis virus: implications to viral replication and neuronal death.

open access: yesPLoS ONE, 2012
The metabolic resources crucial for viral replication are provided by the host. Details of the mechanisms by which viruses interact with host metabolism, altering and recruiting high free-energy molecules for their own replication, remain unknown ...
Leandro Silva da Costa   +3 more
doaj   +1 more source

Homologous Interference Induced by Sindbis Virus [PDF]

open access: yesJournal of Virology, 1974
Homologous interference during Sindbis virus infection has been investigated. Prior infection of either chicken embryo fibroblast or BHK 21 cell cultures results in reduced yields of progeny virions of the superinfecting genotype.
R E, Johnston, K, Wan, H R, Bose
openaire   +2 more sources

Amino acid substitutions in the E2 glycoprotein of Sindbis-like virus XJ-160 confer the ability to undergo heparan sulfate-dependent infection of mouse embryonic fibroblasts

open access: yesVirology Journal, 2010
We have recently demonstrated an essential role of the domain of 145-150 amino acid in the E2 glycoprotein of Sindbis virus in the interaction with cellular heparan sulfate (HS) and in the infection of mouse embryonic fibroblasts (MEF) cells.
Zhu Wuyang   +4 more
doaj   +1 more source

Aura Virus Is a New World Representative of Sindbis-like Viruses [PDF]

open access: yes, 1995
Aura virus is an alphavirus present in Brazil and Argentina that is serologically related to Sindbis virus (present throughout the Old World) and to Western equine encephalitis (WEE) virus (present in the Americas). We have previously shown that WEE is a
Strauss, Ellen G.   +2 more
core   +1 more source

CpG Oligonucleotides Protect Mice From Alphavirus Encephalitis: Role of NK Cells, Interferons, and TNF

open access: yesFrontiers in Immunology, 2020
Arboviruses including alphavirus are responsible for most emerging infectious diseases worldwide. Recent outbreaks of chikungunya virus serve as a stark reminder to their pathogenic potential.
Mohanraj Manangeeswaran   +4 more
doaj   +1 more source

Microassay for Sindbis virus and interferon activity [PDF]

open access: yesJournal of Clinical Microbiology, 1983
A simple and rapid microplaque assay for Sindbis virus was developed which uses microtiter plates and overlay medium consisting of methylcellulose and specific antibody to Sindbis virus. Discrete plaque formation was consistently observed on baby hamster kidney (BHK-15) cells within 24 h. The assay was reproducible, quantitative, and had about the same
R E, Lloyd, D A, Weigent, G J, Stanton
openaire   +2 more sources

Epidemiology of Sindbis virus [PDF]

open access: yes, 2022
Data representing the end-point titers of the samples tested in the neutralization antibody assay.he datasets represent the following: 1. Data representing the end-point titers of the samples tested in the neutralization antibody assay. 2.
Kgothatso Meno (12094847)
core   +1 more source

Genetic determinants of Sindbis virus neuroinvasiveness [PDF]

open access: yesJournal of Virology, 1997
After peripheral inoculation of mice, Sindbis virus replicates in a variety of tissues, leading to viremia. In some cases, the virus can enter the central nervous system (CNS) and cause lethal encephalitis. The outcome of infection is age and virus strain dependent.
J, Dubuisson   +4 more
openaire   +2 more sources

Changes in Cellular mRNA Stability, Splicing, and Polyadenylation through HuR Protein Sequestration by a Cytoplasmic RNA Virus

open access: yesCell Reports, 2013
The impact of RNA viruses on the posttranscriptional regulation of cellular gene expression is unclear. Sindbis virus causes a dramatic relocalization of the cellular HuR protein from the nucleus to the cytoplasm in infected cells.
Michael D. Barnhart   +4 more
doaj   +1 more source

Recombination between Sindbis virus RNAs [PDF]

open access: yesJournal of Virology, 1991
The genome (49S RNA) of Sindbis virus is a positive-strand RNA of 11.7 kb that consists of two domains. The 5' two-thirds of the RNA codes for the proteins required for replication and transcription of the RNA. The 3' one-third codes for the structural proteins.
B G, Weiss, S, Schlesinger
openaire   +3 more sources

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