Results 31 to 40 of about 1,047,175 (209)

A screening for serum markers of arbovirus infections in healthy blood donors from the Volgograd Region

open access: yesИнфекция и иммунитет, 2020
Volgograd region is considered to be endemic West Nile fever (WNF) area due to the established circulation of the West Nile virus (WNV) therein. Some previous independent studies examining samples collected on the territory of the Volgograd region ...
A. О. Negodenkoa   +9 more
doaj   +1 more source

Sindbis Virus Maturation

open access: yesJournal of General Virology, 1973
Sindbis virus, a group A arbovirus, is composed of a nucleocapsid and a glycolipoprotein membrane (Pfefferkorn & Hunter, 1963a; Strauss et al. 1968; Schelle & Pfefferkorn, 1969). The membrane protein is specified by the virus genome (Pfefferkorn & Clifford, 1964; Strauss et al.
C E, Pedersen, B P, Sagik
openaire   +2 more sources

PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response [PDF]

open access: yes, 2009
The double-stranded RNA-activated protein kinase (PKR) is a key regulator of protein translation, interferon (IFN) expression and cell survival. Upon infection of vertebrate cells in continuous culture, the alphavirus Semliki Forest virus (SFV) initiates
Fragkoudis, R.   +20 more
core   +1 more source

Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells [PDF]

open access: yes, 2011
Background: Chikungunya virus (CHIKV) is a mosquito-borne, arthrogenic Alphavirus that causes large epidemics in Africa, South-East Asia and India. Recently, CHIKV has been transmitted to humans in Southern Europe by invading and now established Asian ...
Geertsema, C (Corinne)   +44 more
core   +2 more sources

A survey of mosquito-borne and insect-specific viruses in hospitals and livestock markets in western Kenya.

open access: yesPLoS ONE, 2021
Aedes aegypti and Culex pipiens complex mosquitoes are prolific vectors of arboviruses that are a global threat to human and animal health. Increased globalization and ease of travel have facilitated the worldwide dissemination of these mosquitoes and ...
Tatenda Chiuya   +5 more
doaj   +1 more source

RNA interference targets arbovirus replication in Culicoides cells [PDF]

open access: yes, 2013
Arboviruses are transmitted to vertebrate hosts by biting arthropod vectors such as mosquitoes, ticks and midges. These viruses replicate in both arthropods and vertebrates and are thus exposed to different antiviral responses in these organisms.
Varela, Mariana   +20 more
core   +1 more source

Glycoprotein is enough for sindbis virus-derived DNA vector to express heterogenous genes

open access: yesVirology Journal, 2011
To investigate the necessity and potential application of structural genes for expressing heterogenous genes from Sindbis virus-derived vector, the DNA-based expression vector pVaXJ was constructed by placing the recombinant genome of sindbis-like virus ...
Fu Juanjuan   +6 more
doaj   +1 more source

A novel system for the launch of alphavirus RNA synthesis reveals a role for the Imd pathway in arthropod antiviral response.

open access: yesPLoS Pathogens, 2009
Alphaviruses are RNA viruses transmitted between vertebrate hosts by arthropod vectors, primarily mosquitoes. How arthropods counteract alphaviruses or viruses per se is not very well understood.
Vasanthi Avadhanula   +4 more
doaj   +1 more source

Infectious alphavirus production from a simple plasmid transfection+

open access: yesVirology Journal, 2011
We have developed a new method for producing infectious double subgenomic alphaviruses from plasmids transfected into mammalian cells. A double subgenomic Sindbis virus (TE3'2J) was transcribed from a cytomegalovirus PolII promoter, which results in the ...
Olson Ken E   +4 more
doaj   +1 more source

Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis virus: implications to viral replication and neuronal death.

open access: yesPLoS ONE, 2012
The metabolic resources crucial for viral replication are provided by the host. Details of the mechanisms by which viruses interact with host metabolism, altering and recruiting high free-energy molecules for their own replication, remain unknown ...
Leandro Silva da Costa   +3 more
doaj   +1 more source

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