Results 11 to 20 of about 20,013 (221)
Mathematical Modeling of the Role of Cytokines in Sindbis Virus Treatment of Glioblastoma. [PDF]
CPT Pharmacometrics Syst PharmacolABSTRACT Oncolytic viruses, specifically Sindbis virus (SINV), combined with cytokines show promising results in slowing glioma progression, but a quantitative understanding of their effects remains limited. In this study, we use an ordinary differential equation (ODE) model to examine the effect of adding cytokines to oncolytic SINV therapy.
Makam S, Dobrovolny HM.
europepmc +2 more sources
Detection and Characterization of Sindbis Virus Genotype IV in Mosquitoes From Slovenia. [PDF]
Transbound Emerg DisMosquitoes play a crucial role as vectors of disease pathogens and are among the most socioeconomically important animals in the world. Medically important arboviruses include the Sindbis virus (SINV), which causes chills, skin rashes, and joint pain. Endemic in northern Europe, SINV has been increasingly detected in central Europe. The main objectives
Pozvek P +10 more
europepmc +2 more sources
Journal of Virology, 1972 32 P-labeled ribonucleic acid (RNA) from purified Sindbis virus was examined for the presence of hidden breaks. Viral RNA was treated with acid at p H 2.9 or with formaldehyde and was analyzed on sucrose gradients or by polyacrylamide gel electrophoresis.
B M, Arif, P, Faulkner
openaire +2 more sources
Subgenomic reporter RNA system for detection of alphavirus infection in mosquitoes. [PDF]
PLoS ONE, 2013 Current methods for detecting real-time alphavirus (Family Togaviridae) infection in mosquitoes require the use of recombinant viruses engineered to express a visibly detectable reporter protein.
J Jordan Steel +4 more
doaj +1 more source
Recombination between Sindbis virus RNAs [PDF]
Journal of Virology, 1991 The genome (49S RNA) of Sindbis virus is a positive-strand RNA of 11.7 kb that consists of two domains. The 5' two-thirds of the RNA codes for the proteins required for replication and transcription of the RNA. The 3' one-third codes for the structural proteins.
B G, Weiss, S, Schlesinger
openaire +3 more sources
Wolbachia elevates host methyltransferase expression to block an RNA virus early during infection. [PDF]
PLoS Pathogens, 2017 Wolbachia pipientis is an intracellular endosymbiont known to confer host resistance against RNA viruses in insects. However, the causal mechanism underlying this antiviral defense remains poorly understood.
Tamanash Bhattacharya +2 more
doaj +1 more source
Phosphorylated Proteins of Sindbis Virus [PDF]
Journal of Virology, 1974 The capsid and two membrane proteins of Sindbis virus, grown in chicken cells, contain 0.03 to 0.1 mol of phosphate per mol of protein.
M R, Waite +3 more
openaire +2 more sources
Pathogens, 2022 In the context of climate change, globalization, and enhanced human traveling, arboviruses continue to represent a threat to public health. West Nile and Usutu viruses are mosquito-borne viruses belonging to the Flaviviridae family (Flavivirus genus) and
Mircea Coroian +9 more
doaj +1 more source
Analysis of the Results of Monitoring Arbovirus Infections in the Volgograd Region in 2019
Эпидемиология и вакцинопрофилактика, 2021 Relevance. Natural and climatic conditions, a variety of species composition of arthropods and vertebrates determine the possibility of circulation of arboviruses in the Volgograd region. The existence of natural foci of some arbovirus infections and the
A. O. Negodenko +9 more
doaj +1 more source
Infectious virus-antibody complexes of sindbis virus [PDF]
Infection and Immunity, 1977 Infectious virus-antibody complexes were formed when Sindbis virus was reacted with antibodies raised against purified viral envelope glycoproteins E1 and E2 as well as against preparations of intact virus. Results from rate zonal centrifugation in sucrose gradients of the complex formed with anti-E1 sera showed this complex to be about the same size ...
J, Symington +2 more
openaire +2 more sources