Sindbis Virus Vaccine Platform: A Promising Oncolytic Virus-Mediated Approach for Ovarian Cancer Treatment [PDF]
International Journal of Molecular SciencesThis review article provides a comprehensive overview of a novel Sindbis virus vaccine platform as potential immunotherapy for ovarian cancer patients. Ovarian cancer is the most lethal of all gynecological malignancies. The majority of high-grade serous
Christine Pampeno +2 more
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Agglutination of Sindbis Virus and of Cells Infected with Sindbis Virus by Plant Lectins [PDF]
Journal of Virology, 1973 We have examined the agglutination of Sindbis virus and of chick and hamster cells infected with Sindbis virus by two of the plant lectins, concanavalin A and Ricinus communis agglutinin. Both lectins agglutinate the virus by binding to the polysaccharide chains of the envelope glycoproteins.
Birdwell, Charles R., Strauss, James H.
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Antiviral activity of glycopeptide antibiotics derivates against Sindbis virus
International Journal of Infectious DiseasesIntroduction: Thousands of human infective viruses spread worldwide, yet protective measures exist for only a fraction, with internationally accepted vaccines available for an even smaller subset.
Ms Krisztina Leiner +8 more
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Spread of the Sindbis Virus in Fennoscandia
Проблемы особо опасных инфекций, 2023 In the second half of the last century, a persistent focus of the disease caused by Sindbis virus was formed on the territory of Fennoscandia. In different countries, the disease is called Pogosta disease, Ockelbo disease and Karelian fever.
L. V. Rubis
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Oncolytic Activity of Sindbis Virus with the Help of GM-CSF in Hepatocellular Carcinoma [PDF]
International Journal of Molecular SciencesFan Jia, Fuqiang Xu, Jingjing Fan
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Journal of Virology, 1972 32 P-labeled ribonucleic acid (RNA) from purified Sindbis virus was examined for the presence of hidden breaks. Viral RNA was treated with acid at p H 2.9 or with formaldehyde and was analyzed on sucrose gradients or by polyacrylamide gel electrophoresis.
B M, Arif, P, Faulkner
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Subgenomic reporter RNA system for detection of alphavirus infection in mosquitoes. [PDF]
PLoS ONE, 2013 Current methods for detecting real-time alphavirus (Family Togaviridae) infection in mosquitoes require the use of recombinant viruses engineered to express a visibly detectable reporter protein.
J Jordan Steel +4 more
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Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA [PDF]
Journal of Virology, 1997 Alphaviruses are a well-characterized group of positive-strand RNA viruses. The identification of cis-acting elements in their genomes and their replication strategy have made them useful as vectors for the expression of heterologous genes. In infected cells, the nonstructural proteins, required for replication and transcription of the viral genes, are
I, Frolov, E, Frolova, S, Schlesinger
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Wolbachia elevates host methyltransferase expression to block an RNA virus early during infection. [PDF]
PLoS Pathogens, 2017 Wolbachia pipientis is an intracellular endosymbiont known to confer host resistance against RNA viruses in insects. However, the causal mechanism underlying this antiviral defense remains poorly understood.
Tamanash Bhattacharya +2 more
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Biosynthesis of the Sindbis Virus Carbohydrates [PDF]
Journal of Virology, 1973 The sequence in which sugars are added to the Sindbis virus glycoproteins was studied. Infected cells contain three glycosylated virus-specific proteins: the two virion glycoproteins and the immediate precursor to the smaller virion glycoprotein. Larger Sindbis-specific proteins are not glycosylated.
B M, Sefton, B W, Burge
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