Results 1 to 10 of about 3,551,201 (219)
Clinical Chemistry, 2019 AbstractBACKGROUNDSingle-cell genomics is an approach to investigate cell heterogeneity and to identify new molecular features correlated with clinical outcomes. This approach allows identification of the complexity of cell diversity in a sample without the loss of information that occurs when multicellular or bulk tissue samples are analyzed ...
Paolillo C., Londin E., Fortina P.
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Antifungal Nanomaterials: Current Progress and Future Directions [PDF]
Innovations in Digital Health, Diagnostics, and Biomarkers, 2021 Fungal infection poses a severe threat to human health worldwide resulting in a serious problem in clinic. Due to the limited arsenal of existing antifungal drugs, the nanomaterials were thus regarded as the candidate for developing new antifungal drugs.
Jia-Le Xu +4 more
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Single-Cell Multiomics: Multiple Measurements from Single Cells [PDF]
Trends in Genetics, 2017 Single-cell sequencing provides information that is not confounded by genotypic or phenotypic heterogeneity of bulk samples. Sequencing of one molecular type (RNA, methylated DNA or open chromatin) in a single cell, furthermore, provides insights into the cell's phenotype and links to its genotype.
Macaulay, Iain C. +2 more
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Biotechnology for Biofuels, 2021 Background Triacylglycerol (TAG) is an important storage lipid in organisms, depending on the degree of unsaturation of fatty acid molecules attached to glycerol; it is usually used as the feedstock for nutrition or biodiesel.
Chuanzeng Lan +8 more
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Biotechnology for Biofuels, 2020 Background Phosphopantetheinyl transferase (PPTase) can change the acyl-carrier protein (ACP) from an inactive apo-ACP to an active holo-ACP that plays a key role in fatty acids biosynthesis.
Sen Wang +5 more
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Application of single-cell multi-omics approaches in horticulture research
Molecular Horticulture, 2023 Cell heterogeneity shapes the morphology and function of various tissues and organs in multicellular organisms. Elucidation of the differences among cells and the mechanism of intercellular regulation is essential for an in-depth understanding of the ...
Jun Zhang, Mayra Ahmad, Hongbo Gao
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Arginine methylation as a key post-translational modification in skeletal muscle homeostasis: a review [PDF]
Precision and Future Medicine, 2019 Arginine methylation mediated by protein arginine methyltransferases (PRMTs) has emerged as a key post-translational modification of histone or nonhistone substrates.
Hyebeen Kim +2 more
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Frontiers in Nutrition, 2021 Black chokeberry or aronia (the fruit of Aronia melanocarpa) has been reported to having pharmacological activities against metabolic syndrome, such as hypertension, obesity, diabetes, and pro-inflammatory conditions.
Chae-Eun Yun +14 more
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Exploring functional protein covariation across single cells using nPOP
Genome Biology, 2022 Background Many biological processes, such as cell division cycle and drug resistance, are reflected in protein covariation across single cells. This covariation can be quantified and interpreted by single-cell mass spectrometry with sufficiently high ...
Andrew Leduc +4 more
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Role of Protein Arginine Methyltransferases and Inflammation in Muscle Pathophysiology
Frontiers in Physiology, 2021 Arginine methylation mediated by protein arginine methyltransferases (PRMTs) is a post-translational modification of both histone and non-histone substrates related to diverse biological processes.
Hyun-Kyung So +4 more
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