Results 221 to 230 of about 5,522,894 (323)

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Integrated Single-Cell Analysis Reveals the Heterogeneity of Tumor-Associated Macrophages and Their Implications for Immunotherapy in Colorectal Cancer. [PDF]

J Inflamm Res
Xu G, Fang B, Tang X, Wei Q, Li J.
europepmc   +1 more source

Transcriptome and genome analysis of single disseminated tumor cells: approach to study minimal residual cancer [PDF]

, 2001
Christoph A. Klein, Stefan Seidl, Karina Petat‐Dutter, Oleg Schmidt‐Kittler, Sonja Offner, Gert Riethmüller   +5 more
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Coordination of virulence factors and lifestyle transition in Pseudomonas aeruginosa through single-cell analysis. [PDF]

Commun Biol
Chen H, Malengo G, Wang L, Vogler O, Renner M, Glatter T, Paczia N, Unterweger D, Sourjik V, Diepold A.   +9 more
europepmc   +1 more source

Whole-genome analysis of single disseminated tumor cells isolated from bone marrow of breast cancer patients [PDF]

, 2001
Oleg Schmidt-Kittler, Angela Daskalakis, A. Ahr, Julie Waldispühl, Christoph A. Klein   +4 more
openalex   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Evaluation of Immune Activation in HIV-Infected and Uninfected African Individuals by Single-Cell Analysis of Cytokine Production

, 2001
Matthew Lukwiya, Giuliano Rizzardini, Daria Trabattoni, Stefania Piconi, Marina Saresella, Silvia Declich, Sabrina Fossati, Mario Clerici   +7 more
openalex   +2 more sources

Probability of stealth multiplets in sample-multiplexing for droplet-based single-cell analysis. [PDF]

BMC Genomics
Nakaki F, Sharpe J.
europepmc   +1 more source

Combined single cell RT-PCR analysis with patch clamp recording in acute brain slices

, 2000
Keisuke Tsuzuki, Bertrand Lambolez, Étienne Audinat, James T. Porter, Bruno Cauli, Jean Rossier   +5 more
openalex   +1 more source