Results 251 to 260 of about 763,272 (322)

Correction for Ota et al., Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha. [PDF]

RSC Chem Biol
Xu Z, Sinha A, Pandya DN, Schnicker NJ, Wadas TJ.   +4 more
europepmc   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Single Domain Antibody Inhibitors Target the Coiled Coil Arms of the Bacillus subtilis SMC complex

Gosselin O, Taschner M, Huber-Hürlimann LM, Seeger MA, Gruber S.   +4 more
europepmc   +1 more source

A novel single-domain antibody obtained from immune Bactrian camels against botulinum toxin type A using SPR-based screening method. [PDF]

Heliyon
Hu N, Peng F, Jiang Z, Wang Z, Peng S, Xing C, Liu Y, Li X, Luo L, Chen G, Xiao H, Wang J, Yu J, Liu C, Qiao C, Feng J.   +15 more
europepmc   +1 more source

Improving the biophysical properties of anti-ricin single-domain antibodies

, 2015
Kendrick B. Turner, Jinny L. Liu, Dan Zabetakis, P. Audrey Brozozog Lee, George P. Anderson, Ellen R. Goldman   +5 more
openalex   +2 more sources

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

Fit-for-purpose heterodivalent single-domain antibody for gastrointestinal targeting of toxin B from Clostridium difficile. [PDF]

Protein Sci
Rodriguez Rodriguez ER, Nordvang RT, Petersson M, Rendsvig JKH, Arendrup EW, Fernández Quintero ML, Jenkins TP, Laustsen AH, Thrane SW.   +8 more
europepmc   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

A single domain antibody-based Luminex assay for the detection of SARS-CoV-2 in clinical samples. [PDF]

Front Immunol
Goldman ER, Sugiharto VA, Shriver-Lake LC, Garcia AM, Wu SJ, Jenkins SA, Chen HW.   +6 more
europepmc   +1 more source