Results 131 to 140 of about 7,329,727 (241)

Oral Microalgae‐Laden Hydrogels Modulating the Intestinal Microbiota Metabolism for Acute Alcohol‐Induced Liver Injury Therapy

Small, EarlyView.
A food‐grade microalgae‐laden hydrogel (FMH) enables efficient in situ microalgae cultivation and serves as an oral therapeutic platform for acute alcohol‐induced liver injury. FMH improves alcohol tolerance, alleviates oxidative stress, inflammation, and lipid metabolic disorders, restores gut microbial homeostasis, and provides synergistic ...
Zhixin Hu, Hongtao Wu, Xuanqi Liu, Xinxu Huang, Linli Jiang, Lei Liu, Xiaojie Li, Yawen Yao, Fengzheng Gao, Kui Zeng, Jiajing Zhou   +10 more
wiley   +1 more source

Revealing Airflow–Particle Dynamics in Dry Powder Inhalers

Small, EarlyView.
An integrated framework combining device and formulation characterization, CFD–DEM simulations, and interpretable machine learning is established. This framework reveals how airflow and particle interactions govern powder dispersion across prevailing dry powder inhalers.
Jiale Chen, Ziyi Fan, Qingliang Yang, Yuanyuan Shao, Dongbing Li, Xiaoyang Wei, Xiang Luo, Kaiqi Shi, Gang Yang, Gensheng Yang, Ying Ma, Yuqing Ye, Jesse Zhu   +12 more
wiley   +1 more source

Cost-Effectiveness of FF/UMEC/VI vs BUD/GLY/FOR in Moderate-to-Very Severe COPD

BMC Health Services Research
Background COPD is a significant cause of morbidity and mortality worldwide and in Colombia. Although single-inhaler triple therapies have demonstrated superior clinical benefits in patients with previous exacerbations, their economic value in middle ...
Jefferson Antonio Buendía, Oscar Muñoz-Mejía, Luisa Fernanda Manrique Acevedo, Carlos Andres Celis-Preciado   +3 more
doaj   +1 more source

Medication adherence and persistence in chronic obstructive pulmonary disease patients receiving triple therapy in a USA commercially insured population

International Journal of COPD, 2019
Michael Bogart,1 Richard H Stanford,1 François Laliberté,2 Guillaume Germain,2 Jennifer W Wu,2 Mei Sheng Duh3 1GlaxoSmithKline plc, Research Triangle Park, NC, USA; 2Groupe d’Analyse, Ltée, Montréal, QC, Canada ...
Bogart M, Stanford RH, Laliberté F, Germain G, Wu JW, Duh MS   +5 more
doaj  

Real-World Study of Single-Inhaler Triple Therapy with Fluticasone Furoate/Umeclidinium/Vilanterol on Asthma Control in the US. [PDF]

J Asthma Allergy, 2023
Bogart M, Germain G, Laliberté F, Mahendran M, Duh MS, DiRocco K, Noorduyn SG, Paczkowski R, Balkissoon R.   +8 more
europepmc   +1 more source

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

Small, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan, Bei Song, Chengyun Liu, Peiyu Zhong, Quan Zhou, Xiaofang Zhao, Guangyu Gao, Xinyue Zhang, Xueke Guang, Tianci Yao, Ting Liu, Hao Zhang, Xinqi Diao, Weilin Lu   +13 more
wiley   +1 more source

Cyanogenic Compounds, Physicochemical Parameters and Metals in Water From Cassava Processing Areas: A Study in the Brazilian Amazon, Using Multivariate Analysis

Environmental Toxicology, EarlyView.
ABSTRACT This study evaluated the water quality of artesian wells and effluents generated in cassava processing in a rural area of Bragança, Pará, with emphasis on physicochemical parameters, multielement composition, and cyanogenic compounds. The well water presented specific nonconformities, highlighting pH values below the recommended level and high
Alana Coêlho Maciel, Mariane Gama Nabiça, Luciana Pinheiro Santos, Thiago de Melo e Silva, Elivaldo Nunes Modesto Junior, Heronides Adonias Dantas Filho, Charles Miller de Souza Borges, Kelly das Graças Fernandes Dantas, Simone de Fátima Pinheiro Pereira, Ivan Carlos da Costa Barbosa, Beni Jequicene Mussengue Chaúque, Rosinelson da Silva Pena, Nayara Macêdo Peixoto Araújo, Alessandra Santos Lopes   +13 more
wiley   +1 more source

Cytogenotoxic and Molecular Assessment of Pyrethrins on Non‐Target Allium cepa Roots

Environmental Toxicology, EarlyView.
ABSTRACT The pyrethrins, which form a part of naturally occurring insecticidal chemicals derived from chrysanthemum flowers, not only provide rapid knockdown of a broad spectrum of insect pests but are also widely used in integrated pest management due to a generally favorable safety profile, largely attributed to low mammalian toxicity.
Yudum Yeltekin Uğur, Rahsan Ilikci‐Sagkan, Recep Liman   +2 more
wiley   +1 more source

Single maintenance and reliever therapy (SMART) of asthma: a critical appraisal [PDF]

, 2010
A. P. Greening, Barnes, NC, Chapman, KR, Pedersen, S, S. Pedersen, N. C. Barnes, Greening, AP, Jones, PW, K. R. Chapman, P. W. Jones   +9 more
core   +1 more source

Efficacy and Safety of Single-Inhaler Triple Therapy in COPD: A Systematic Review with Implications for UK Clinical Practice

This systematic review evaluates the efficacy and safety of single-inhaler triple therapy (LAMA/LABA/ICS) compared to dual therapy or monotherapy in adults with Chronic Obstructive Pulmonary Disease (COPD). The review synthesizes evidence from randomized
Nawaid Ahmad, Praveenkumar Katarki
core   +4 more sources