Results 141 to 150 of about 7,329,727 (241)

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Perspectives on Treatment Decisions, Preferences, and Adherence and Long-Term Management in Asthma and COPD: A Qualitative Analysis of Patient, Caregiver, and Healthcare Provider Insights

Patient Preference and Adherence
Miguel Román-Rodríguez,1,2 Ilona McMullan,3 Michelle Warner,3 Christopher H Compton,3 Ruth Tal-Singer,4 Jean M Orlow,5 MeiLan K Han6 1Centro de Salud Dra. Teresa Pique, Mallorca, Spain; 2Instituto de Investigación Sanitaria de las Islas Baleares (IdISBa),
Román-Rodríguez M, McMullan I, Warner M, Compton CH, Tal-Singer R, Orlow JM, Han MK   +6 more
doaj  

Large‐Scale Applications of Plasma Technologies: Progresses and Challenges

High Voltage, EarlyView.
ABSTRACT Plasma technologies convert electrical power into energetic electrons, ions, reactive species, radiation and heat, thereby breaking through the bottleneck of purely thermal or chemical routes and bringing impressive changes to our world. This roadmap reviews the progress and challenges of plasma technologies from a large‐scale and application ...
Pankaj Attri, Liuyang Bai, Dmitry Batomunkuev, Xueke Che, Guoxing Chen, Zhitong Chen, Wei Cui, Liguang Dou, Zhi Fang, Yangyang Fu, Fausto Gallucci, Yiming Guo, Bangdou Huang, Yinghong Li, Sirui Li, Hua Liang, Liangliang Lin, Dingxin Liu, Xiangyang Liu, Xinpei Lu, Ruonan Ma, Lanlan Nie, Guanghui Niu, Yuge Ouyang, Tao Shao, Jing Sun, Yong Tang, Xin Tu, Sergey P. Vashchenko, Hang Wang, Xianjie Wang, Anke Weidenkaff, Yun Wu, Haohan Xie, Shaojun Xu, Zongxian Yang, Fangli Yuan, Cheng Zhang, Hao Zhang, Jishen Zhang, Shuai Zhang, Yejian Zhang, Zhe Zhang, Zhibo Zhang, Peng Zhao, Shicheng Zhao, Linlin Zhong, Renwu Zhou, Zhenhua Zhou, Xi Zhu, Yifei Zhu, Haohua Zong   +51 more
wiley   +1 more source

Kinetics of Antibody Responses and Effector Cell Sensitivity After High Dose Birch Extract Nasal Challenge

Allergy, EarlyView.
High‐dose birch‐extract nasal challenge induced synchronous peaks at 4 weeks in serum specific IgE (sIgE) and basophil sensitivity. Mast cell sensitivity via tSPT and sIgG1 and sIgG4 responses peaked later, at 6–8 weeks. Preseasonal allergen exposure attenuated seasonal sIgE increase and prevented further rise in tSPT sensitivity.
N. J. Campion, S. Villazala‐Merino, C. Morgenstern, L. Nemec, V. Stanek, A. Tu, M. Zghaebi, J. Toth, R. Fröschl, T. Perkmann, M. Bastl, K. Gangl, S. Schneider, H. Breiteneder, R. Ristl, M. Focke‐Tejkl, R. Valenta, V. Niederberger‐Leppin, J. Eckl‐Dorna   +18 more
wiley   +1 more source

Impact of Increased Use of Single-Inhaler Triple Therapies on COPD Exacerbation Rates, Mortality, and Total Costs: PROMETHEUS France

International Journal of COPD
Gaëtan Deslee,1 Héloïse Russo,2 Caroline Fabry-Vendrand,2 David Koskas,2 Gabriel Thabut,2 John P Bell,3 Melissa Caplen,4 Prachi Devendra Bhatt,4 Jennifer Carioto,4 Bruce Pyenson,4 Pierre-Régis Burgel5 1Service de Pneumologie, INSERM UMRS-1250, Hospital ...
Deslee G, Russo H, Fabry-Vendrand C, Koskas D, Thabut G, Bell JP, Caplen M, Bhatt PD, Carioto J, Pyenson B, Burgel PR   +10 more
doaj  

Effectiveness of Extrafine Single Inhaler Triple Therapy in Chronic Obstructive Pulmonary Disease (COPD) in Germany - The TriOptimize Study. [PDF]

Int J Chron Obstruct Pulmon Dis, 2022
Gessner C, Trinkmann F, Bahari Javan S, Hövelmann R, Bogoevska V, Georges G, Nudo E, Criée CP.   +7 more
europepmc   +1 more source

Efficacy and Safety of Intralymphatic Immunotherapy With Grass Allergoid and Microcrystalline Tyrosine: A Double‐Blind Randomised Placebo‐Controlled Trial

Allergy, EarlyView.
This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić, Stephan C. Flory, Claudia C. V. Lang, Emma C. Widmer, Alexandra Chabot, Johannes M. Schmid, Tobias Andermatt, David Melillo, Bjarke Hviid‐Vyff, Maibritt Mardahl, Peter Schmid‐Grendelmeier, Thomas M. Kündig, Hans Jürgen Hoffmann, Pål Johansen   +13 more
wiley   +1 more source

PROMETHEUS: Long-Term Exacerbation and Mortality Benefits of Implementing Single-Inhaler Triple Therapy in the US COPD Population. [PDF]

J Health Econ Outcomes Res, 2023
Criner G, Martinez F, Gandhi H, Pyenson B, Feigler N, Emery M, Gupta U, Vaduganathan M.   +7 more
europepmc   +1 more source

Nasal Epithelial Immune Signatures Are Associated With Age‐Dependent Asthma Trajectories in Early Life

Allergy, EarlyView.
Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth, Sabina Illi, Helen Charles, Madlen Oelsner, Amr A. Gabr, Ulrich M. Zissler, Anna Erb, Martin Feuerherd, Felix Drost, Maren Büttner, Benjamin Schubert, Nicole Maison, Jimmy Omony, Markus Weckmann, Ruth Grychtol, Anna‐Maria Dittrich, Svenja Foth, Chrysanthi Skevaki, Tobias Trojan, Silke van Koningsbruggen‐Rietschel, Gesine Hansen, Thomas Bahmer, Klaus F. Rabe, Folke Brinkmann, Matthias Volkmar Kopp, Ulrike Protzer, Adam M. Chaker, Bianca Schaub, Erika von Mutius, Carsten B. Schmidt‐Weber, the ALLIANCE Study Group as part of the German Center for Lung Research (DZL), Mira Bürk, Sybille Contento, Markus Ege, Kristina Gottschau, Silvia Gschwendtner, Alexander Hose, Lena Lagally, Michael Schloter, Lena Ullemeyer, Esther Zeitlmann, Mustafa Abdo, Heike Biller, Karoline I. Gaede, Clara Haug, Nikolas Jacobs, Anne‐Marie Kirsten, Inke R. König, Lea Kronziel, Gyde Nissen, Frauke Pedersen, Loana Pennerd, Isabell Ricklefs, Vera Veith, Henrik Watz, Marie Bickes, Mifflin‐Rae Calvero, David S. DeLuca, Svenja Gaedcke, Anika Habener, Christine Happle, Adan Chari Jirmo, Bin Liu, Lennart Riemann, Nicolaus Schwerk, Inga Jerrentrup, Harald Renz, Stefanie Weber, Miguel A. Alejandre Alcazar, Samira Blau, Ernst Rietschel, Jan‐Christoph Thomassen   +71 more
wiley   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source