Comparative Effectiveness of Step-up Therapies in Children with Asthma Prescribed Inhaled Corticosteroids : A Historical Cohort Study [PDF]
This work was supported by the Respiratory Effectiveness Group. Acknowledgments We thank the Respiratory Effectiveness Group for funding this work, Annie Burden for assistance with statistics, and Simon Van Rysewyk and Lisa Law for assistance with ...
Murray, Claire S. +4 more
core +2 more sources
Cost-effectiveness analysis of umeclidinium bromide/vilanterol 62.5/25 mcg versus tiotropium/olodaterol 5/5 mcg in symptomatic patients with chronic obstructive pulmonary disease: A Spanish National Healthcare System perspective [PDF]
Background: A head-to-head study demonstrated the superiority of once-daily umeclidinium bromide/vilanterol (UMEC/VI) 62.5/25 mcg on trough forced expiratory volume in 1 s (FEV1) versus once-daily tiotropium/olodaterol (TIO/OLO) 5/5 mcg in symptomatic ...
Alcázar-Navarrete, B. +9 more
core +4 more sources
Diagnosis and Pharmacotherapy of Stable Chronic Obstructive Pulmonary Disease : The Finnish Guidelines [PDF]
Peer ...
Anthonisen NR +34 more
core +2 more sources
Lai CC, Chen CH, Lin CYH, Wang CY, Wang YH. Int J Chron Obstruct Pulmon Dis. 2019;14:1539–1548. The authors advised that they have introduced errors while preparing this article which were oversighted by all authors.On page 1541, in Results section, Risk of moderate or severe COPD exacerbation; (rate ratio, 0.81; 95% CI, 0.73 to 0.89, I2=29 ...
Lai CC +4 more
openaire +9 more sources
Gema Requena,1 Victoria Banks,2,* Alexandrosz Czira,1 Robert Wood,2 Theo Tritton,2 Rosie Wild,2 Chris Compton,1 Afisi S Ismaila3,4 1Value Evidence and Outcomes, GSK, R&D Global Medical, Brentford, Middlesex, UK; 2Real-World Evidence, Adelphi Real ...
Requena G +7 more
doaj
Triple therapy with inhaled corticosteroid (ISC) / long-acting β2 agonist (LABA) / long-acting muscarinic antagonist (LAMA) in single inhaler expanded the possibilities for prevention of chronic obstructive pulmonary disease (COPD) exacerbations ...
L. A. Shpagina +7 more
doaj +1 more source
Effects of adding Tiotropium or Aclidinium as triple therapy using impulse oscillometry in COPD [PDF]
INTRODUCTION: Long-acting muscarinic antagonists confer improvements in spirometry when used in addition to inhaled corticosteroids and long-acting beta-agonists (ICS/LABA) in COPD.
A Gavalda +22 more
core +3 more sources
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Inhaled corticosteroids for chronic obstructive pulmonary disease-the shifting treatment paradigm [PDF]
Chronic obstructive pulmonary disease (COPD) guidelines suggest using inhaled corticosteroids (ICS) in patients with severe airflow limitation or those at high risk of exacerbations.
Duerden M +8 more
core +2 more sources
Cost-Effectiveness of Once-Daily Single-Inhaler COPD Triple Therapy in Spain: IMPACT Trial
Given between-country differences in healthcare systems, treatment costs, and disease management guidelines, country-specific cost-effectiveness analyses are important. This study evaluated the cost-effectiveness of once-daily fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) versus FF/VI and UMEC/VI among patients with symptomatic chronic ...
Victoria Federico Paly +8 more
openaire +5 more sources

