Results 51 to 60 of about 7,329,727 (241)

The IMPACT of tripleversusdual single-inhaler therapy on exacerbations of COPD [PDF]

Breathe, 2018
In the IMPACT trial, triple inhalation therapy resulted in a lower rate of moderate or severe COPD exacerbations compared with either dual therapy with ICS/LABA or LAMA/LABA, but pneumonia rates were increased. http://ow.ly/pYJn30mgpFp.
openaire   +2 more sources

Combination formoterol and budesonide as maintenance and reliever therapy versus inhaled steroid maintenance for chronic asthma in adults and children (Review) [PDF]

, 2009
Background Traditionally inhaled treatment for asthma has been considered as preventer and reliever therapy. The combination of formoterol and budesonide in a single inhaler introduces the possibility of using a single inhaler for both prevention and ...
Christopher J Cates, Lasserson, TJ, Toby J Lasserson, Cates, CJ   +3 more
core   +1 more source

Association between blood procollagen III N-terminal propeptide, granulocyte-macrophage colony-stimulating factor and triple therapy in single inhaler efficacy for chronic obstructive pulmonary disease re-exacerbation prevention

Сибирский научный медицинский журнал
Triple therapy with inhaled corticosteroid (ISC) / long-acting β2 agonist (LABA) / long-acting muscarinic antagonist (LAMA) in single inhaler expanded the possibilities for prevention of chronic obstructive pulmonary disease (COPD) exacerbations ...
L. A. Shpagina, О. S. Kotova, I. S. Shpagin, Е. М. Loktin, G. V. Kuznetsova, S. A. Karmanovskaya, L. A. Panacheva, E. V. Anikina   +7 more
doaj   +1 more source

The Effects Of Single Inhaler Triple Therapy Vs Single Inhaler Dual Therapy Or Separate Triple Therapy For The Management Of Chronic Obstructive Pulmonary Disease: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials [Corrigendum]

International Journal of COPD, 2019
Lai CC, Chen CH, Lin CYH, Wang CY, Wang YH. Int J Chron Obstruct Pulmon Dis. 2019;14:1539–1548. The authors advised that they have introduced errors while preparing this article which were oversighted by all authors.On page 1541, in Results section, Risk of moderate or severe COPD exacerbation; (rate ratio, 0.81; 95% CI, 0.73 to 0.89, I2=29 ...
Lai CC, Chen CH, Lin CYH, Wang CY, Wang YH   +4 more
openaire   +9 more sources

INTREPID: single- versus multiple-inhaler triple therapy for COPD in usual clinical practice [PDF]

, 2021
Introduction Real-world trial data comparing single- with multiple-inhaler triple therapy (MITT) in COPD patients are currently lacking. The effectiveness of once-daily single-inhaler fluticasone furoate (FF)/umeclidinium (UMEC)/vilanterol (VI) and MITT ...
Dawn Midwinter, Jose M. Marin, Halpin, David M. G., Halpin, David M.G., Janwillem W.H. Kocks, Tabberer, Maggie, Sally Worsley, Snowise, Neil G., Martin, Neil, Neil G. Snowise, Marin, Jose M., Maggie Tabberer, Chris Compton, Kocks, Janwillem W.H., Worsley, Sally, Afisi S. Ismaila, Compton, Chris, Neil Martin, Elaine Irving, David M.G. Halpin, Beeh, Kai-Michael, Irving, Elaine, Midwinter, Dawn, Kai-Michael Beeh, Ismaila, Afisi S., Kocks, Janwillem W. H.   +25 more
core   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Treatment Patterns, Healthcare Utilization and Clinical Outcomes of Patients with Chronic Obstructive Pulmonary Disease Initiating Single-Inhaler Long-Acting β2-Agonist/Long-Acting Muscarinic Antagonist Dual Therapy in Primary Care in England

International Journal of COPD, 2023
Gema Requena,1 Victoria Banks,2,* Alexandrosz Czira,1 Robert Wood,2 Theo Tritton,2 Rosie Wild,2 Chris Compton,1 Afisi S Ismaila3,4 1Value Evidence and Outcomes, GSK, R&D Global Medical, Brentford, Middlesex, UK; 2Real-World Evidence, Adelphi Real ...
Requena G, Banks V, Czira A, Wood R, Tritton T, Wild R, Compton C, Ismaila AS   +7 more
doaj  

Effectiveness of Extrafine Single Inhaler Triple Therapy in Chronic Obstructive Pulmonary Disease (COPD) in Germany – The TriOptimize Study

, 2022
Christian Gessner,1 Frederik Trinkmann,2,3 Sanaz Bahari Javan,4 Raimund Hövelmann,4 Valentina Bogoevska,4 George Georges,5 Elena Nudo,6 Carl-Peter Criée7 1Pneumologische Praxis Leipzig, Universitätsklinikum Leipzig, Institut für Klinische Immunologie ...
Georges G, Criée CP, Trinkmann F, Hövelmann R, Bogoevska V, Gessner C, Nudo E, Bahari Javan S   +7 more
core  

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Efficacy and Safety of Single-Inhaler Triple Therapy in COPD: A Systematic Review

This systematic review evaluates the efficacy and safety of single-inhaler triple therapy (LAMA/LABA/ICS) compared to dual therapy or monotherapy in adults with Chronic Obstructive Pulmonary Disease (COPD).
Nawaid Ahmad, Praveenkumar Katarki
core   +7 more sources