Results 61 to 70 of about 4,782 (272)

Perceived Impacts and Predictors of Cannabis Products used by Rheumatology Patients in Alberta: A Multivariable Analysis of Cross‐sectional Survey Data

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among rheumatology patients, and their associations with patient factors, patient reported perceived side effects and positive impacts. Methods An online survey (delivered from March to November 2022) was distributed by Alberta Health Services to ...
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

The effect of adding inhaled corticosteroids to tiotropium and long-acting beta(2)-agonists for chronic obstructive pulmonary disease (Review) [PDF]

, 2011
BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropiumare commonly used, either on their own or in combination, for managing persistent symptoms of chronic obstructive pulmonary disease ...
Aaron, Aaron, Agarwal, Akazawa, Appleton, Barr, Beeh, Berger, Briggs, Calverley, Dalal, Effing, Higgins, Hutchinson, Johnson, Kaplan, Lacasse, Meer, Najafzadeh, Najafzadeh, Nannini, Nannini Luis, Proskocil, Rodrigo, Rodrigo, Roisman, Singh, Singh, Tanaka, Tashkin, Wallukat, Welsh, Yang   +32 more
core   +1 more source

Characteristics of COPD patients treated with single‑inhaler triple therapy in real-life clinical practice

Bratislava Medical Journal, 2021
Inflammation associated with chronic obstructive pulmonary disease (COPD) causes narrowing of the airways and destruction of the lung parenchyma. The triple therapy (ICS+LABA+LAMA) may improve lung function, patient‑reported outcomes, and exacerbation risk in a specified subset of GOLD group D patients.
S, Lassan, J, Keszegh, M, Lassanova
openaire   +2 more sources

Biocompatible but Antibacterial Mechanism of Graphene Oxide for Sustainable Antibiotics

Advanced Functional Materials, EarlyView.
Graphene oxide (GO) exhibits selective antibacterial activity through specific interactions between its oxygen functional groups and bacterial membrane phospholipid POPG, causing membrane destabilization while maintaining biocompatibility. Model membrane studies and infected wound models in mice and pigs demonstrate effective bacterial suppression and ...
Sujin Cha, Ju Yeon Chung, Seungju Yang, Seung Cheol Lee, Chan Woo Lee, Colin Wing‐Lok Cheng, Jun Beom Kim, Nam Jun Kim, Ayoung Park, Heewon Choi, Junpyo Sinn, Ralph Weissleder, Nicholas A. Kotov, Myungeun Seo, Hyun Jung Chung, Sang Ouk Kim   +15 more
wiley   +1 more source

FULFIL Trial: Once-Daily Triple Therapy in Patients with Chronic Obstructive Pulmonary Disease [PDF]

, 2017
RATIONALE: Randomized data comparing triple therapy with dual inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA) therapy in patients with chronic obstructive pulmonary disease (COPD) are limited.
Barnacle, H, Birk, R, Brealey, N, Lipson, DA, Locantore, N, Lomas, DA, Ludwig-Sengpiel, A, Mohindra, R, Pascoe, SJ, Tabberer, M, Zhu, C-Q   +10 more
core  

Long-acting beta(2)-agonist in addition to tiotropium versus either tiotropium or long-acting beta(2)-agonist alone for chronic obstructive pulmonary disease [PDF]

, 2012
BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropium are commonly used for managing persistent symptoms of chronic obstructive pulmonary disease.
Aaron, Aaron, Appleton, Arievich, Barr, Bateman, Berger, Brusasco, Calverley, Cazzola, Cheyne, Effing, Fujimoto, Gross, Hacken, Higgins, Hutchinson, Johnson, Kaplan, Karner, Lacasse, Mahler, Mahler, Marco, Meer, Meyer, Najafzadeh, Najafzadeh, New, Noord, Noord, Noord, Proskocil, Rodrigo, Roisman, Singh, Tanaka, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Vogelmeier, Vogelmeier, Wallukat, Welsh   +47 more
core   +1 more source

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Characteristics of New Users of Single- and Multiple-Inhaler Triple Therapy for COPD in Primary Care in England

International Journal of COPD, 2022
Kieran J Rothnie,1 Sandra Joksaite,1 Leah B Sansbury,2 Chris Compton,3 Valentina Di Boscio,4 Afisi S Ismaila5,6 1Value Evidence and Outcomes, R&D Global Medical, GlaxoSmithKline, London, UK; 2Value Evidence and Outcomes, R&D Global Medical ...
Rothnie KJ, Joksaite S, Sansbury LB, Compton C, Di Boscio V, Ismaila AS   +5 more
doaj  

Why small particle fixed dose triple therapy? An excursus from COPD pathology to pharmacological treatment evolution

Therapeutic Advances in Respiratory Disease, 2022
Although bronchodilators are the cornerstone in chronic obstructive pulmonary disease (COPD) therapy, the treatment with a single-agent bronchodilator may not provide adequate symptoms control in COPD.
Fulvio Braido, Angelo G. Corsico, Davide Paleari, Alessio Piraino, Luca Cavalieri, Nicola Scichilone   +5 more
doaj   +1 more source

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma (Protocol) [PDF]

, 2014
Background Long-acting muscarinic antagonists (LAMA), a class of drugs with proven effectiveness in chronic obstructive pulmonary disease (COPD), are being considered as an add-on option for adults with asthma whose condition is uncontrolled on inhaled ...
Adams, Adams, Bateman, Chauhan, Chong, Ducharme, Ducharme, Gosens, Karner, Lipworth, Moulton, Ni, Tee, Verhamme, Wise   +14 more
core   +2 more sources