Results 51 to 60 of about 5,980,056 (304)

Non-astigmatic Alexandrite ring laser design with wavelength-tunable single-longitudinal-mode operation [PDF]

, 2020
This work presents a study of a fully nonastigmatic design of a single-longitudinal-mode, wavelength-tunable, unidirectional alexandrite ring laser cavity and assessment of its performance compared to more complex laser design requiring astigmatism ...
Sheng, xin, Minassian, ara, Damzen, Michael, Sathian, juna, Tawy, goronwy   +4 more
core   +1 more source

Direct generation of genuine single-longitudinal-mode narrowband photon pairs

New Journal of Physics, 2015
The practical prospect of quantum communication and information processing relies on sophisticated single-photon pairs, which feature a controllable waveform, narrow spectrum, excellent purity, fiber compatibility, and miniaturized design.
Kai-Hong Luo, Harald Herrmann, Stephan Krapick, Benjamin Brecht, Raimund Ricken, Viktor Quiring, Hubertus Suche, Wolfgang Sohler, Christine Silberhorn   +8 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Repetition rate tunable single-longitudinal-mode acoustic-optical Q-switched nanosecond laser

Results in Physics, 2023
Repetition rate-tunable single-longitudinal-mode (SLM) lasers are in wide demand for light detection and ranging. This study proposes an SLM acoustic-optical Q-switched Nd:YVO4 laser based on a short-cavity scheme.
Yifu Chen, Zhenxu Bai, Duo Jin, Yindong Li, Yaoyao Qi, Jie Ding, Bingzheng Yan, Kun Wang, Yulei Wang, Zhiwei Lu   +9 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Wavelength-Switchable Single-Longitudinal- Mode Thulium-Doped Fiber Laser With Sampled Fiber Bragg Grating

IEEE Access, 2021
A wavelength-switchable single-longitudinal-mode thulium-doped fiber laser using a sampled fiber Bragg grating is proposed in this study. The laser can be switched between three single-wavelength and three dual-wavelength modes of operation.
Wenguo Han, Fengping Yan, Ting Feng, Luna Zhang, Biao Guan, Qi Qin, Ying Guo, Ting Li, Hong Zhou, Yuping Suo   +9 more
doaj   +1 more source

Injection-seeded single-longitudinal-mode Ti:Sapphire laser with no active stabilization

Optics Express, 2020
We report on the first injection-seeded nanosecond Ti:Sapphire laser that demonstrates a stable single-longitudinal-mode operation with no feedback loop for active cavity stabilization. The short cavity generates 6-mJ transform-limited pulses at a wavelength of 807 nm and with a slope efficiency of 43%.
I G, Marienko, M, Zhi, A I, Khizhnyak, A V, Sokolov   +3 more
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Single-photon circularly polarized single-mode vortex beams

, 2023
Generation of single photons carrying spin and orbital angular momenta (SAM and OAM) opens enticing perspectives for exploiting multiple degrees of freedom for high-dimensional quantum systems.
Changying Zhao (5990135), Danylo Komisar (11105128), Xujing Liu (12467659), Sergey I. Bozhevolnyi (1466827), Yinhui Kan (8728011), Shailesh Kumar (441797)   +5 more
core   +1 more source