Results 61 to 70 of about 7,974,684 (289)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Longitudinal mode-coupling instabilities of proton bunches in the CERN Super Proton Synchrotron
Physical Review Accelerators and Beams, 2023 In this paper, we study single-bunch instabilities observed in the CERN Super Proton Synchrotron (SPS). According to the linearized Vlasov theory, radial or azimuthal mode-coupling instabilities result from a coupling of bunch-oscillation modes, which ...
Ivan Karpov
doaj +1 more source
IEEE Access, 2021 A wavelength-switchable single-longitudinal-mode thulium-doped fiber laser using a sampled fiber Bragg grating is proposed in this study. The laser can be switched between three single-wavelength and three dual-wavelength modes of operation.
Wenguo Han +9 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Impact of Mode Switching on Nonresponse and Bias in a Multimode Longitudinal Study of Young Adults
Survey Research Methods, 2023 Young adults are generally hard to survey, presenting researchers with numerous difficulties. They are hard to locate and contact due to high mobility. They are hard to persuade and exhibit high levels of resistance to survey participation. As a result,
Ting Yan +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Nonlinear longitudinal/transversal modal interactions in highly extensible suspended cables [PDF]
, 2008 Recent research literature mostly deals with nonlinear resonant dynamics of low-extensible cables involving transversal modes. Herein, we aim to investigate geometrically nonlinear longitudinal/transversal modal interactions in highly extensible ...
Rega, G., Srinil, N.
core +4 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Non-astigmatic Alexandrite ring laser design with wavelength-tunable single-longitudinal-mode operation [PDF]
, 2020 This work presents a study of a fully nonastigmatic design of a single-longitudinal-mode, wavelength-tunable, unidirectional alexandrite ring laser cavity and assessment of its performance compared to more complex laser design requiring astigmatism ...
Sheng, xin +4 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source