Results 11 to 20 of about 5,030,666 (315)

songuno1/single-molecule-assay: Single-molecule assay analysis

open access: yes, 2023
Single-molecule assay analysis tool for "Transcriptional pause extension benefits the stand-by rather than catch-up Rho-dependent termination"
Eunho Song
core   +1 more source

Single-Molecule Nanomagnets [PDF]

open access: yesAnnual Review of Condensed Matter Physics, 2010
Single-molecule magnets straddle the classical and quantum mechanical worlds, displaying many fascinating phenomena. They may have important technological applications in information storage and quantum computation. We review the physical properties of two prototypical molecular nanomagnets, Mn12-acetate and Fe8: Each behaves as a rigid, spin-10 ...
Friedman, Jonathan R.   +1 more
openaire   +2 more sources

Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2

open access: yesNature Communications, 2022
Single-molecule FRET measurements provide detailed insights into the conformational states and dynamics of human Argonaute 2 that are required for its function at the core of the eukaryotic RNA silencing pathway.
Sarah Willkomm   +6 more
doaj   +1 more source

Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88

open access: yesBMC Biology, 2018
Background Higher-order self-assembly of proteins, or “prion-like” polymerisation, is now emerging as a simple and robust mechanism for signal amplification, in particular within the innate immune system, where the recognition of pathogens or danger ...
Ailís O’Carroll   +11 more
doaj   +1 more source

Spontaneous Confinement of mRNA Molecules at Biomolecular Condensate Boundaries

open access: yesCells, 2023
Cellular biomolecular condensates, termed ribonucleoprotein (RNP) granules, are often enriched in messenger RNA (mRNA) molecules relative to the surrounding cytoplasm.
Rebecca T. Perelman   +3 more
doaj   +1 more source

Single-molecule nano-optics at low temperature [PDF]

open access: yes, 2006
The work presented in this thesis involves experiments on single molecules at low temperature. At low temperature, many disturbing temperature activated processes are frozen out, resulting in extremely sharp zero-phonon lines in the fluorescence ex ...
Butter, Jacqueline Yvonne Paula
core   +1 more source

Force transmission by retrograde actin flow-induced dynamic molecular stretching of Talin

open access: yesNature Communications, 2023
Force transmission at integrin-based adhesions is important for cell migration and mechanosensing. Talin is an essential focal adhesion (FA) protein that links F-actin to integrins.
Sawako Yamashiro   +5 more
doaj   +1 more source

Direct-laser writing for subnanometer focusing and single-molecule imaging

open access: yesNature Communications, 2022
Focus-locking improves localization precision in single-molecule microscopy, but fiducials are often deposited at random and provide limited 3D compensation.
Simao Coelho   +4 more
doaj   +1 more source

A mechanism with severing near barbed ends and annealing explains structure and dynamics of dendritic actin networks

open access: yeseLife, 2022
Single molecule imaging has shown that part of actin disassembles within a few seconds after incorporation into the dendritic filament network in lamellipodia, suggestive of frequent destabilization near barbed ends.
Danielle Holz   +5 more
doaj   +1 more source

Single‐molecule genomics [PDF]

open access: yesThe Journal of Pathology, 2009
AbstractThe term ‘single‐molecule genomics’ (SMG) describes a group of molecular methods in which single molecules are detected or sequenced. The focus on the analysis of individual molecules distinguishes these techniques from more traditional methods, in which template DNA is cloned or PCR‐amplified prior to analysis. Although technically challenging,
Frank, McCaughan, Paul H, Dear
openaire   +2 more sources

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